FIGURE

Fig. S3

ID

ZDB-FIG-070131-6

Publication

Lepilina et al., 2006 - A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration

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Fig. S3

Epicardial Expression of fgfrs during Heart Regeneration. (A) At 3 dpa, fgfr2 and fgfr4 are expressed in contiguous domains of atrial epicardial cells (violet stains,arrowheads), distant from the injured ventricular apex (not shown). (B) Double in situ hybridization colocalizing fgfr4 (red) and tbx18 (green) at 14 dpa, demonstrating fgfr4 expression in epicardial-derived cells. fgfr4 was expressed in the tbx18-positive cells closest to the apical edge of the regenerate (boxes). Scale bar = 100 μm.

Expression Data

Genes:	fgfr2 fgfr4 tbx18
Fish:	WT
Condition:	resection: ventricular myocardium
Anatomical Terms:	epicardium heart
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Cell, 127(3), Lepilina, A., Coon, A.N., Kikuchi, K., Holdway, J.E., Roberts, R.W., Burns, C.G., and Poss, K.D., A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration, 607-619, Copyright (2006) with permission from Elsevier. Full text @ Cell