FIGURE

Fig. 5

ID

ZDB-FIG-060829-2

Publication

Jasuja et al., 2006 - bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axis

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Fig. 5

Specific role for BMP1 in zebrafish dorsoventral patterning. (A and B) Embryos either uninjected (A) or injected (B) with bmp1 RNA are shown at 55 hpf. (C and D) Embryos injected with both bmp1 MO1 and tll1 MO in the absence (C) or presence (D) of human BMP1 RNA are shown at 24 hpf. (E–H) Embryos in which in situ hybridization for chordin has been performed are shown at 75% epiboly, to the right of embryos injected with the same RNAs and/or MOs. Animal views are shown for E–H, with dorsal to the right. (I) RT-PCR analysis is shown for control uninjected embryos (C) or embryos injected with bmp1 SP-MO (M).

Expression Data

Gene:	chrd
Fish:	WT WT + MO2-tll1 + MO3-bmp1a
Knockdown Reagents:	MO2-tll1 MO3-bmp1a
Anatomical Term:	margin
Stage:	75%-epiboly

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 123(7), Jasuja, R., Voss, N., Ge, G., Hoffman, G.G., Lyman-Gingerich, J., Pelegri, F., and Greenspan, D.S., bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axis, 548-558, Copyright (2006) with permission from Elsevier. Full text @ Mech. Dev.