FIGURE
Fig. 3
- ID
- ZDB-FIG-060203-18
- Publication
- Cunliffe et al., 2006 - Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS
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Fig. 3
Expression of nkx2.2a in the ventral hindbrain is smoothened-dependent but up-regulated in hdac1 mutant embryos. (A–H) Expression of nkx2.2a in hindbrain of (A,C,E,G) wild-type sibling, (B) smoothened (smoh) mutant and (D,F,H) hdac1 mutant embryos at (A,B) 32 hpf, (C,D) 28 hpf, (E,F,G,H) 50 hpf. Panels A–F show transverse sections through the hindbrain of embryos at the level of rhombomere 5 and panels G,H show dorsal views of (G) wild-type and (H) hdac1 mutant hindbrain, demonstrating that expression of nkx2.2a in the ventral medial hindbrain is stably increased by loss of hdac1 function. |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Anatomical Term: | |
| Stage Range: | Prim-5 to Long-pec |
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Mechanisms of Development, 123(1), Cunliffe, V.T., and Casaccia-Bonnefil, P., Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS, 24-30, Copyright (2006) with permission from Elsevier. Full text @ Mech. Dev.