FIGURE

Fig. 3

ID

ZDB-FIG-060203-18

Publication

Cunliffe et al., 2006 - Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS

Other Figures

(all 7)

All Figure Page

Back to All Figure Page

Fig. 3

Expression of nkx2.2a in the ventral hindbrain is smoothened-dependent but up-regulated in hdac1 mutant embryos. (A–H) Expression of nkx2.2a in hindbrain of (A,C,E,G) wild-type sibling, (B) smoothened (smoh) mutant and (D,F,H) hdac1 mutant embryos at (A,B) 32 hpf, (C,D) 28 hpf, (E,F,G,H) 50 hpf. Panels A–F show transverse sections through the hindbrain of embryos at the level of rhombomere 5 and panels G,H show dorsal views of (G) wild-type and (H) hdac1 mutant hindbrain, demonstrating that expression of nkx2.2a in the ventral medial hindbrain is stably increased by loss of hdac1 function.

Expression Data

Gene:	nkx2.2a
Fish:	WT hdac1^hi1618Tg smo^hi1640Tg
Anatomical Term:	hindbrain
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Mechanisms of Development, 123(1), Cunliffe, V.T., and Casaccia-Bonnefil, P., Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS, 24-30, Copyright (2006) with permission from Elsevier. Full text @ Mech. Dev.