FIGURE

Fig. 6

ID

ZDB-FIG-051031-6

Publication

Challa et al., 2005 - Robo3 isoforms have distinct roles during zebrafish development

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Fig. 6

RNA expression patterns of robo3 isoforms during the second day of development. Lateral (A, C) and dorsal (B, D) views of the head showing whole-mount RNA in situ hybridizations for robo3var1 and robo3var2 at 48 hpf. (A, B) Diffuse expression of robo3var1 in the midbrain (double asterisks in A) with stronger expression in the cerebellum (B, arrows) and hindbrain (B, bar). (C, D) Distinct and robust expression of robo3var2 in the cerebellum (D, arrows) and hindbrain (D, bar). Notice the lack of expression of both isoforms in the tectum (A and C, asterisks). Patches of robo3var2 expressing cells are present in the diencephalic regions (C, arrowhead) and in the telencephalon (D, arrowheads).

Expression Data

Gene:	robo3
Fish:	WT + MO1-robo3 + MO2-robo3
Knockdown Reagents:	MO1-robo3 MO2-robo3
Anatomical Terms:	cerebellum diencephalon hindbrain midbrain telencephalon
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 122(10), Challa, A.K., McWhorter, M.L., Wang, C., Seeger, M.A., and Beattie, C.E., Robo3 isoforms have distinct roles during zebrafish development, 1073-1086, Copyright (2005) with permission from Elsevier. Full text @ Mech. Dev.