ZFIN ID: ZDB-FIG-050314-5
Loeb-Hennard et al., 2005 - Prominent transcription of zebrafish N-myc (nmyc1) in tectal and retinal growth zones during embryonic and early larval development. Gene expression patterns : GEP   5(3):341-347 Full text @ Gene Expr. Patterns
Anatomical Terms:
Stage Range: Shield to Long-pec

Fig. 2 Expression of zebrafish nmyc1 highlights restricted neural and endodermal domains at embryonic stages. Expression of nmyc1 revealed by in situ hybridization with a digoxygenin-labelled nmyc1 antisense riboprobe on whole-mount embryos (anterior left; lateral views in A,C,F,H; dorsal views in B, C inset, F inset; stages indicated bottom left of each panel). (D) and (E) are cross-sections at the 20-somite stage at the midbrain level to compare dlx2 and nmyc1 expression in neural crest cells (one half of the embryos only is shown). (G) and (I) are sections of the embryos shown in (F) and (H), respectively, at the levels indicated. Expression at early stages is ubiquitous but progressively resolves into restricted positive domains in endodermal derivatives (g), migrating neural crest cells (arrows in D, E), branchial arches (ba) and limited brain territories. The latter include the epiphysis (ep), the eye (e) and the midbrain-hindbrain (MH, bracket in C,F,H). MH expression is restricted to the alar plate (al) and absent from the basal plate (bas) (see G,I), thus labels the presumptive optic tectum (tec) and dorsal anterior hindbrain.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
mycn WT standard conditions Shield whole organism ISH
Bud neural plate ISH
10-13 somites hindbrain ISH
10-13 somites immature eye ISH
10-13 somites midbrain ISH
Prim-5 endoderm ISH
Prim-5 epiphysis ISH
Prim-5 hindbrain ISH
Prim-5 immature eye ISH
Prim-5 midbrain ISH
Prim-5 optic tectum ISH
Prim-5 pharyngeal arch 3-7 skeleton ISH
Long-pec eye ISH
Long-pec optic tectum ISH
Long-pec pharyngeal arch 3-7 skeleton ISH
Antibody Labeling Details No data available
Phenotype Details No data available
ZFIN wishes to thank the journal Gene expression patterns : GEP for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Gene expression patterns : GEP, 5(3), Loeb-Hennard, C., Kremmer, E., and Bally-Cuif, L., Prominent transcription of zebrafish N-myc (nmyc1) in tectal and retinal growth zones during embryonic and early larval development, 341-347, Copyright (2005) with permission from Elsevier. Full text @ Gene Expr. Patterns