Gene

mycn

ID
ZDB-GENE-020711-1
Name
MYCN proto-oncogene, bHLH transcription factor
Symbol
mycn Nomenclature History
Previous Names
  • N-myc (1)
  • fb57a02 (1)
  • nmyc1 (1)
  • wu:fb57a02 (1)
  • zgc:85706 (1)
  • zN-myc (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have DNA binding activity; DNA-binding transcription factor activity; and protein dimerization activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in several structures, including immature eye; nervous system; pectoral fin bud; pharyngeal arch; and pronephric duct. Human ortholog(s) of this gene implicated in Feingold syndrome. Orthologous to human MYCN (MYCN proto-oncogene, bHLH transcription factor).
Genome Resources
Note
None
Expression
All Expression Data
9 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mycn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Feingold syndrome Alliance Feingold syndrome 1 164280
Associated With mycn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR012682 Transcription regulator Myc, N-terminal
Family IPR002418 Transcription regulator Myc
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Transcription regulator Myc Transcription regulator Myc, N-terminal
UniProtKB:Q9PSJ0
UniProtKB:Q6PBB3 486
UniProtKB:Q5GFD4 456
UniProtKB:A0A0A0MPF8 503
UniProtKB:Q6NWH6 455
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations