Gene

mycn

ID
ZDB-GENE-020711-1
Name
MYCN proto-oncogene, bHLH transcription factor
Symbol
mycn Nomenclature History
Previous Names
  • N-myc (1)
  • fb57a02 (1)
  • nmyc1 (1)
  • wu:fb57a02 (1)
  • zgc:85706 (1)
  • zN-myc (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have DNA binding activity; DNA-binding transcription factor activity; and protein dimerization activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Feingold syndrome. Is expressed in several structures, including immature eye; nervous system; pectoral fin bud; pharyngeal arch; and pronephric duct. Orthologous to human MYCN (MYCN proto-oncogene, bHLH transcription factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mycn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Feingold syndrome Alliance Feingold syndrome 1 164280
Associated With mycn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR012682 Transcription regulator Myc, N-terminal
Family IPR002418 Transcription regulator Myc
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Transcription regulator Myc Transcription regulator Myc, N-terminal
UniProtKB:Q9PSJ0
UniProtKB:Q6PBB3 486
UniProtKB:Q6NWH6 455
UniProtKB:Q5GFD4 456
UniProtKB:A0A0A0MPF8 503
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations