ZFIN ID: ZDB-FIG-050310-4
Rentzsch et al., 2003 - Specific and conserved roles of TAp73 during zebrafish development. Gene   323:19-30 Full text @ Gene
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Prim-5
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-5 to Day 5

Fig. 6 Loss-of-function experiments. (A–D) In situ hybridization revealing p73 expression in embryos injected with 5 mismatch-control MO (5mm MO) (A, C), or in TAp73 morphant embryos injected with TAp73 MO1 (p73MO) at the one-cell stage (B, D); (A, B) lateral views, (C, D) dorsal views on head. Arrowheads point to missing caudo-medial cells. (E, F) Alcian blue staining of 5 mismatch control MO-injected (E) and TAp73 MO1-injected embryo (F), ventral views on head; anterior to the left. Numbers indicate pharyngeal arches 1–7 (mandibular, hyoid and five gill arches). Abbreviations: bb, basibranchial; bh, basihyal; cb, ceratobranchial; ch, ceratohyal; hs, hyosymplectic; pq, palatoquadrate.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
tp73 WT + MO1-tp73 standard conditions Prim-5 unspecified ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-tp73 standard conditions Prim-5 olfactory placode morphology, abnormal
WT + MO1-tp73 standard conditions Prim-5 telencephalon morphology, abnormal
WT + MO1-tp73 standard conditions Prim-5 telencephalon development disrupted, abnormal
WT + MO1-tp73 standard conditions Day 5 basibranchial decreased size, abnormal
WT + MO1-tp73 standard conditions Day 5 basibranchial undulate, abnormal
WT + MO1-tp73 standard conditions Day 5 basihyal cartilage decreased size, abnormal
WT + MO1-tp73 standard conditions Day 5 basihyal cartilage undulate, abnormal
WT + MO1-tp73 standard conditions Day 5 ceratobranchial cartilage decreased size, abnormal
WT + MO1-tp73 standard conditions Day 5 ceratohyal cartilage displaced, abnormal
WT + MO1-tp73 standard conditions Day 5 cranial cartilage malformed, abnormal
WT + MO1-tp73 standard conditions Day 5 cranial cartilage shape, abnormal
WT + MO1-tp73 standard conditions Day 5 hyosymplectic cartilage mislocalised posteriorly, abnormal
WT + MO1-tp73 standard conditions Day 5 palatoquadrate cartilage mislocalised posteriorly, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Gene for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Gene, 323, Rentzsch, F., Kramer, C., and Hammerschmidt, M., Specific and conserved roles of TAp73 during zebrafish development, 19-30, Copyright (2003) with permission from Elsevier. Full text @ Gene