ZFIN Morpholino: MO1-tp73

Target Location

Genome Build: GRCz11Chromosome: 8

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-tp73

No data available

Phenotype

Phenotype resulting from MO1-tp73

Phenotype	Fish	Figures
basibranchial decreased size, abnormal	WT + MO1-tp73	Fig. 6 from Rentzsch et al., 2003
basibranchial undulate, abnormal	WT + MO1-tp73	Fig. 6 from Rentzsch et al., 2003
basihyal cartilage decreased size, abnormal	WT + MO1-tp73	Fig. 6 from Rentzsch et al., 2003
basihyal cartilage undulate, abnormal	WT + MO1-tp73	Fig. 6 from Rentzsch et al., 2003
ceratobranchial cartilage decreased size, abnormal	WT + MO1-tp73	Fig. 6 from Rentzsch et al., 2003

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Phenotype of all Fish created by or utilizing MO1-tp73

Phenotype	Fish	Conditions	Figures
basihyal cartilage decreased size, abnormal	WT + MO1-tp73	standard conditions	Fig. 6 from Rentzsch et al., 2003
basibranchial decreased size, abnormal	WT + MO1-tp73	standard conditions	Fig. 6 from Rentzsch et al., 2003
telencephalon morphology, abnormal	WT + MO1-tp73	standard conditions	Fig. 6 from Rentzsch et al., 2003
basibranchial undulate, abnormal	WT + MO1-tp73	standard conditions	Fig. 6 from Rentzsch et al., 2003
cranial cartilage malformed, abnormal	WT + MO1-tp73	standard conditions	Fig. 6 from Rentzsch et al., 2003

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Citations

Include unpublished citations

Pyati, U.J., Gjini, E., Carbonneau, S., Lee, J.S., Guo, F., Jette, C.A., Kelsell, D.P., and Look, A.T. (2011) p63 Mediates an Apoptotic Response to Pharmacological and Disease-Related ER Stress in the Developing Epidermis. Developmental Cell. 21(3):492-505
Davidson, W., Ren, Q., Kari, G., Kashi, O., Dicker, A.P., and Rodeck, U. (2008) Inhibition of p73 function by Pifithrin-α as revealed by studies in zebrafish embryos. Cell cycle (Georgetown, Tex.). 7(9):1224-1230
Sidi, S., Sanda, T., Kennedy, R.D., Hagen, A.T., Jette, C.A., Hoffmans, R., Pascual, J., Imamura, S., Kishi, S., Amatruda, J.F., Kanki, J.P., Green, D.R., D'Andrea, A.A., and Look, A.T. (2008) Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3. Cell. 133(5):864-877
Nowak, M., Köster, C., and Hammerschmidt, M. (2005) Perp is required for tissue-specific cell survival during zebrafish development. Cell death and differentiation. 12(1):52-64
Rentzsch, F., Kramer, C., and Hammerschmidt, M. (2003) Specific and conserved roles of TAp73 during zebrafish development. Gene. 323:19-30

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