CRISPR

CRISPR4-ace2

ID

ZDB-CRISPR-251010-2

Name

CRISPR4-ace2

Previous Names

None

Target

ace2 (1)

Sequence

5' - GGCCTGCTGTCAGACTGTGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
syu701	ace2

Expression

Gene expression in Wild Types + CRISPR4-ace2

No data available

Phenotype

Phenotype resulting from CRISPR4-ace2

No data available

Phenotype of all Fish created by or utilizing CRISPR4-ace2

Phenotype	Fish	Conditions	Figures
liver igf2r expression increased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 5 from Wu et al., 2025
liver igf1rb expression increased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 5 from Wu et al., 2025
muscle L-serine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle L-glutamine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle area density, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle L-arginine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle L-tryptophan decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle hydroxyproline increased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
liver hk1 expression increased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 5 from Wu et al., 2025
intestine host-mediated modulation of intestinal microbiota composition decreased process quality, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 3 from Wu et al., 2025
muscle L-cysteine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
liver ugp2a expression increased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 5 from Wu et al., 2025
muscle L-alanine increased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle L-tyrosine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
whole organism decreased length, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 1 from Wu et al., 2025
liver hk2 expression increased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 5 from Wu et al., 2025
muscle L-methionine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle valine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle amino acid decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle L-lysine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle L-leucine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
hypophysis gh1 expression decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 1 from Wu et al., 2025
blood plasma amino acid decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle L-proline decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
whole organism decreased weight, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 1 from Wu et al., 2025
muscle L-glutamic acid decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
liver pklr expression increased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 5 from Wu et al., 2025
muscle L-aspartic acid decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
muscle L-isoleucine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025
liver igf1ra expression increased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 5 from Wu et al., 2025
muscle L-phenylalanine decreased amount, abnormal	ace2^{syu701/syu701}	standard conditions	Fig. 2 from Wu et al., 2025

Citations