Gene

ace2

ID

ZDB-GENE-041114-6

Name

angiotensin I converting enzyme 2

Symbol

ace2 Nomenclature History

Previous Names

zgc:92514 (1)

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have peptidase activity, acting on L-amino acid peptides. Predicted to be involved in proteolysis. Predicted to localize to extracellular space and plasma membrane. Human ortholog(s) of this gene implicated in diabetic retinopathy and hypertension. Orthologous to human ACE2 (angiotensin I converting enzyme 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ace2 Human Ortholog

No data available

Associated With ace2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR031588	Collectrin domain
Family	IPR001548	Peptidase M2, peptidyl-dipeptidase A

Domain Details Per Protein

Protein	Length	Collectrin domain	Peptidase M2, peptidyl-dipeptidase A
UniProtKB:A0A8M2BGN5 InterPro	807
UniProtKB:E7F9E5 InterPro	818
UniProtKB:Q5U380 InterPro	785

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ace2-201 (1) Ensembl	Ensembl		2,856 nt	Select Tool ZFIN BLAST
mRNA	ace2-202 (1) Ensembl	Ensembl		2,870 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations