ZFIN is now using GRCz12tu for Genomic Data
Gene
ace2
- ID
- ZDB-GENE-041114-6
- Name
- angiotensin I converting enzyme 2
- Symbol
- ace2 Nomenclature History
- Previous Names
-
- zgc:92514 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable carboxypeptidase activity and metallopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in several cellular components, including apical plasma membrane; cilium; and extracellular region. Predicted to be active in extracellular space and plasma membrane. Is expressed in brain; gill; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including avian influenza; cerebral malaria; hypertension (multiple); respiratory syncytial virus infectious disease; and severe acute respiratory syndrome. Orthologous to human ACE2 (angiotensin converting enzyme 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Collectrin domain | Peptidase M2, peptidyl-dipeptidase A |
|---|---|---|---|---|
| UniProtKB:A0A8M2BGN5 | InterPro | 807 | ||
| UniProtKB:E7F9E5 | InterPro | 818 | ||
| UniProtKB:Q5U380 | InterPro | 785 | ||
| UniProtKB:A0AB32TXH6 | InterPro | 783 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers