CRISPR
CRISPR1-pln1
- ID
- ZDB-CRISPR-190304-6
- Name
- CRISPR1-pln1
- Previous Names
-
- CRISPR1-pln
- Pln_p.R14Del (1)
- Target
- Sequence
-
5' - GGCACGGGCGGCCATTCGG - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
The second "G" in the sequence does not match the current sequence in Ensembl. The PAM site was "CGG" at the 3' end.
- Genome Resources
- None
Target Location
Constructs
No data available
Genomic Features
Expression
Gene expression in Wild Types + CRISPR1-pln1
No data available
Phenotype
Phenotype resulting from CRISPR1-pln1
No data available
Phenotype of all Fish created by or utilizing CRISPR1-pln1
No data available
Citations
- Kamel, S.M., van Opbergen, C.J.M., Koopman, C.D., Verkerk, A.O., Boukens, B.J.D., de Jonge, B., Onderwater, Y.L., van Alebeek, E., Chocron, S., Polidoro Pontalti, C., Weuring, W.J., Vos, M.A., de Boer, T.P., van Veen, T.A.B., Bakkers, J. (2021) Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model of phospholamban R14del cardiomyopathy. Nature communications. 12:7151
- Tessadori, F., Roessler, H.I., Savelberg, S.M.C., Chocron, S., Kamel, S.M., Duran, K.J., van Haelst, M.M., van Haaften, G., Bakkers, J. (2018) Effective CRISPR/Cas9-based nucleotide editing in zebrafish to model human genetic cardiovascular disorders. Disease models & mechanisms. 11(10):
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