ZFIN ID: ZDB-GENE-990706-8

Gene Name:GLI-Kruppel family member GLI2a
Gene Symbol: gli2a

Previous Names: gli2, wu:fc85b05(1) , etID12892.9(1) , you too, you-too, yot, fc85b05
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	18 figure(s) from 10 publications
Directly submitted expression data:	6 figure(s) (22 images) from Thisse et al., 2005 [eu801]
Wild Type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Protruding-mouth (72.00h-96.00h, 3.5mm)
	adenohypophyseal placode, anterior neural plate ... (all 29)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   11 genotypes
Allele(s):   s406, ty119, ty17a, unspecified_gli2a

Phenotype: (current status)

Data:	20 figures from 14 publications
Observed in:	adaxial cell, adenohypophysis, adenohypophysis morphogenesis, adrenocorticotropic hormone secreting cell, adrenocorticotropin hormone secreting cell differentiation ... (all 39)

Knockdown reagents: MO1-gli2a (1) ,   MO2-gli2a (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Molecular Function	nucleic acid binding (more)
Biological Process	central nervous system neuron differentiation (more)
Cellular Component	intracellular

All GO Terms (26)

Protein Families, Domains and Sites:

InterPro:IPR007087 (1) InterPro:IPR013087 (1) InterPro:IPR015880 (1)

PROSITE:PS00028 (1) PROSITE:PS50157 (1)

Pfam:PF00096 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

gli2a Contained in	[BAC] CH211-61D13 (1)    (order this) , DKEY-25L23 (1)    (order this)
gli2a Encodes	[EST] eu801 (1) , fc85b05 (1) [cDNA] MGC:195099 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_130967 (1)	6070 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX548071 (1)	223099 bp	- Select Tool - MegaBLAST
Polypeptide	UniProtKB:B0S6T1 (1)	1439 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:8091 (1)
All Sequence Information (17)

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OTHER  gli2a  GENE / MARKER PAGES:

Entrez Gene:30154 (1)

VEGA:OTTDARG00000020879 (1)

Ensembl(Zv8):ENSDARG00000025641 (1)

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MAPPING INFORMATION:

LG:  9    Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL	XH
Zebrafish	gli2a	9
Human	GLI2	2 (q14)	OMIM:165230 Entrez Gene:2736
Mouse	Gli2	1 (63.00 cM)	MGI:95728 Entrez Gene:14633
Orthology Details

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CITATIONS   (88)