Gene

gli2a

ID
ZDB-GENE-990706-8
Name
GLI family zinc finger 2a
Symbol
gli2a Nomenclature History
Previous Names
  • gli2
  • etID12892.9 (1)
  • fc85b05
  • wu:fc85b05 (1)
  • yot
  • you too
  • you-too
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Exhibits sequence-specific DNA binding activity. Involved in several processes, including animal organ development; nervous system development; and regionalization. Localizes to non-motile cilium and nucleus. Is expressed in several structures, including central nervous system; digestive system; head; mesoderm; and neural plate. Human ortholog(s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Orthologous to human GLI2 (GLI family zinc finger 2).
Genome Resources
Note
None
Expression
All Expression Data
30 figures from 21 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
45 figures from 28 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gli2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Culler-Jones syndrome Alliance Culler-Jones syndrome 615849
holoprosencephaly 9 Alliance Holoprosencephaly 9 610829
Associated With gli2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR043359 C2H2-type zinc-finger protein GLI-like
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length C2H2-type zinc-finger protein GLI-like Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:B0S6T1 1439
UniProtKB:Q98SN1 1357
UniProtKB:Q9YGS4 1439
UniProtKB:A0A2R8QMX9 1443
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-gli2a polyclonal Rabbit
  • WB
5
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations