ZFIN ID: ZDB-GENE-990415-171

Gene Name:cadherin 2, neuronal
Gene Symbol: cdh2

Previous Names: lyr(1) , neural cadherin, ncad, n-cadherin(1) , parachute(1) , wu:fb47h04, glass onion(1) , zncad, pac(1) , labyrinth(1) , glo(1)
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	25 figure(s) from 17 publications
Wild Type Stages, Structures:	Blastula:Sphere (4.00h-4.33h) to Adult (90d-730d, breeding adult)
	anterior macula, anterior neural keel ... (all 41)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   34 genotypes
Allele(s):   fr7, hi1389Tg, hi3096Tg, hi3644Tg, m117 ... (all 18)

Phenotype: (current status)

Data:	42 figures from 10 publications
Observed in:	anterior neural keel, apoptosis, axial mesoderm, brain, convergent extension involved in neural plate elongation ... (all 49)

Knockdown reagents: MO1-cdh2 (2) ,   MO2-cdh2 (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	dorsal convergence (more)
Cellular Component	catenin complex (more)
Molecular Function	calcium ion binding

All GO Terms (39)

Protein Families, Domains and Sites:

InterPro:IPR000233 (1) InterPro:IPR002126 (1) InterPro:IPR009124 (1) InterPro:IPR014868 (1) InterPro:IPR015919 (1) InterPro:IPR020894 (1)

PROSITE:PS00232 (1) PROSITE:PS50268 (1)

Pfam:PF00028 (1) Pfam:PF01049 (1) Pfam:PF08758 (1)

Gene Product Description

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ANTIBODIES:

ab1-pan-Cadherin (10)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

cdh2 Contained in	[BAC] DKEYP-38F5 (1)
cdh2 Encodes	[EST] fb47h04 [cDNA] MGC:158217 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131081 (1)	4672 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR759908 (1)	164351 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:Q1L8K3 (1)	893 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:75081 (1)
All Sequence Information (14)

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OTHER  cdh2  GENE / MARKER PAGES:

Entrez Gene:30291 (1)

VEGA:OTTDARG00000015513 (1)

Ensembl(Zv8):ENSDARG00000018693 (1)

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MAPPING INFORMATION:

LG:  20  Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL
Zebrafish	cdh2	20
Human	CDH2	18 (q11.2)	OMIM:114020 Entrez Gene:1000
Mouse	Cdh2	18 (6.00 cM)	MGI:88355 Entrez Gene:12558
Orthology Details

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CITATIONS   (77)