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General Information
ZIRC
ZFIN: Gene: atoh1a
ZFIN ID: ZDB-GENE-990415-17

Gene Name:atonal homolog 1a
Gene Symbol: atoh1a
Previous Names: zath1(1) , Atoh1.1(1) , ath1, atoh1, Zath1a(1) , ZATH-1(1) , zgc:136417
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 30 figure(s) from 23 publications
Wild Type Stages, Structures: Segmentation:10-13 somites (14.00h-16.00h) to Larval:Protruding-mouth (72.00h-96.00h, 3.5mm)
  cerebellum, fourth ventricle ... (all 13)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   2 genotypes
Allele(s):   fh282, unrec_atoh1a
Phenotype: (current status)
  Data: 4 figures from 3 publications
  Observed in: hair cell, kinocilium, neuromast, neuromast hair cell, posterior lateral line neuromast
Knockdown reagents: MO1-atoh1a (1) ,   MO2-atoh1a (1) ,   MO3-atoh1a (1) ,   MO4-atoh1a (1) ,   MO5-atoh1a (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process auditory receptor cell differentiation (more)
Cellular Component nucleus
Molecular Function transcription regulator activity
All GO Terms (9)

Protein Families, Domains and Sites:
  • InterPro:IPR001092 (1)
  • InterPro:IPR011598 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • Loading Transcript Data...

    Gene Product Description


    CONSTRUCTS WITH SEQUENCE FROM atoh1a:
    Tg(atoh1a:Gal4TA4)

    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    atoh1a Contained in [BAC] CH211-247L22 (1)    (order this)
    atoh1a Encodes [cDNA] MGC:136417 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131091 (1) 906 bp
    Genomic GenBank:AL807792 (1) 160553 bp
    Polypeptide UniProtKB:Q1ED07 (1) 292 aa
    Sequence Clusters UniGene:566 (1)
    All Sequence Information (9)

    OTHER  atoh1a  GENE / MARKER PAGES:

  • Entrez Gene:30303 (1)
  • VEGA:OTTDARG00000020311 (1)
  • Ensembl(Zv8):ENSDARG00000055294 (1)

  • MAPPING INFORMATION:
      LG:  8    Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish atoh1a  8
    Human ATOH1  4 (q22)
  • OMIM:601461
  • Entrez Gene:474
  • Mouse Atoh1  6 (29.69 cM)
  • MGI:104654
  • Entrez Gene:11921
  • Orthology Details

    CITATIONS   (49)