Gene
wnt2
- ID
- ZDB-GENE-980526-416
- Name
- wingless-type MMTV integration site family member 2
- Symbol
- wnt2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have frizzled binding activity. Involved in hepatocyte proliferation and swim bladder development. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and urinary system cancer. Is expressed in several structures, including nervous system; optic cup; optic vesicle; otic vesicle; and swim bladder bud. Orthologous to human WNT2 (Wnt family member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65730 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Poulain et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Wnt | Wnt-2 protein | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:Q92048
|
350 |
Interactions and Pathways
No data available
Plasmids
No data available