ZFIN ID: ZDB-GENE-980526-416

Gene Name:wingless-type MMTV integration site family member 2
Gene Symbol: wnt2

Previous Names: ZfWnt2(1) , etID309852.18(1)
Nomenclature History

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GENE EXPRESSION:(current status)

Directly submitted expression data:	7 figure(s) (11 images) from Thisse et al., 2004 [MGC:65730]
Wild Type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.00h-144.00h, 3.9mm, 6 teeth)
	neural tube, neuron ... (all 8)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   2 genotypes
Allele(s):   hu2847, hu2848

Phenotype: (current status)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Molecular Function	signal transducer activity
Biological Process	Wnt receptor signaling pathway (more)
Cellular Component	extracellular region (more)

All GO Terms (6)

Protein Families, Domains and Sites:

InterPro:IPR005816 (1) InterPro:IPR005817 (1) InterPro:IPR009140 (1) InterPro:IPR018161 (1)

PROSITE:PS00246 (1)

Pfam:PF00110 (1)

Gene Product Description

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

wnt2 Contained in	[BAC] CH211-238N5 (1)    (order this) , DKEY-270I2 (1)    (order this)
wnt2 Contains	[SNP] rs3728908 (1) , rs3728909 (1)
wnt2 Encodes	[cDNA] MGC:65730 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_130950 (1)	1509 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX470130 (1)	191401 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:Q1LX47 (1)	350 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:378 (1)
All Sequence Information (15)

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OTHER  wnt2  GENE / MARKER PAGES:

Entrez Gene:30127 (1)

VEGA:OTTDARG00000013718 (1)

Ensembl(Zv8):ENSDARG00000041117 (1)

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MAPPING INFORMATION:

LG:  18  Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA
Zebrafish	wnt2	18
Human	WNT2	7 (q31.2)	OMIM:147870 Entrez Gene:7472
Mouse	Wnt2	6 (4.20 cM)	MGI:98954 Entrez Gene:22413
Orthology Details

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CITATIONS   (20)