ZFIN ID: ZDB-GENE-980526-39

Gene Name:carbonic anhydrase
Gene Symbol: cahz

Previous Names: wu:cegs2190, id:ibd5016(1) , wu:fj65c09, zCA2-like b(1) , zCAb(1) , cah, cb588(1)
Nomenclature History

---

GENE EXPRESSION:(current status)

All expression data:	29 figure(s) from 12 publications
Directly submitted expression data:	10 figure(s) (33 images) from Rauch et al., 2003 [cegs2190]
	6 figure(s) (16 images) from Thisse et al., 2001 [cb588]
	1 figure(s) (1 images) from Kudoh et al., 2001 [ibd5016]
Wild Type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
	blood, blood island ... (all 26)
Curated microarray expression:	GEO  (1)

---

MUTANTS AND TARGETED KNOCKDOWNS:

Phenotype: (current status)

Knockdown reagent: MO1-cahz (1)

---

GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	hypotonic salinity response (more)
Molecular Function	carbonate dehydratase activity (more)

All GO Terms (6)

Protein Families, Domains and Sites:

InterPro:IPR001148 (1) InterPro:IPR018338 (1) InterPro:IPR018440 (1)

PROSITE:PS00162 (1) PROSITE:PS51144 (1)

Pfam:PF00194 (1)

EC:4.2.1.1 (1)

Gene Product Description

---

SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

cahz Contained in	[BAC] CH211-121G18 (1)    (order this)
cahz Encodes	[EST] cb588 (1)    (order this) , cegs2190 (2)    (order this) , fj65c09 (1) , ibd5016 (1)    (order this) [cDNA] MGC:77128 (1)    (order this)

---

SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131110 (1)	1574 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX927106 (1)	147604 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:Q92051 (1)	260 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:32297 (1)
All Sequence Information (12)

---

OTHER  cahz  GENE / MARKER PAGES:

Entrez Gene:30331 (1)

VEGA:OTTDARG00000019781 (1)

Ensembl(Zv8):ENSDARG00000011166 (1)

---

MAPPING INFORMATION:

LG:  2    Details

View Map: Merged  Individual Panels

---

ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA
Zebrafish	cahz	2
Human	CA2	8 (q22)	OMIM:259730 Entrez Gene:760
Mouse	Car2	3 (10.50 cM)	MGI:88269 Entrez Gene:12349
Orthology Details

---

CITATIONS   (39)