ZFIN ID: ZDB-GENE-980526-330

Gene Name:caudal type homeo box transcription factor 4
Gene Symbol: cdx4

Previous Names: cdx1(1) , cad1, id:ibd2812, zfcad1, caudal, id:ibd5107, zf-cad1(1) , CHUNP6923, cb546(1) , caudal homeobox 1(1) , id:ibd1215, kugelig, kgg
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	42 figure(s) from 21 publications
Directly submitted expression data:	4 figure(s) (4 images) from Kudoh et al., 2001 [ibd5107]
	3 figure(s) (3 images) from Kudoh et al., 2001 [ibd1215]
	4 figure(s) (4 images) from Kudoh et al., 2001 [ibd2812]
	6 figure(s) (24 images) from Thisse et al., 2001 [cb546]
Wild Type Stages, Structures:	Blastula:1k-cell (3.00h-3.33h) to Adult (90d-730d, breeding adult)
	axial hypoblast, DEL ... (all 24)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   12 genotypes
Allele(s):   hi2092Tg, hi2188aTg, hi2617Tg, tl240a, tv205c

Phenotype: (current status)

Data:	19 figures from 9 publications
Observed in:	anatomical system, anterior/posterior pattern formation, ball, cell migration, convergent extension involved in axis elongation ... (all 34)

Knockdown reagents: MO1-cdx4 (1) ,   MO2-cdx4 (1) ,   MO3-cdx4 (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	anterior/posterior axis specification (more)
Cellular Component	nucleus
Molecular Function	DNA binding (more)

All GO Terms (18)

Protein Families, Domains and Sites:

InterPro:IPR000047 (1) InterPro:IPR001356 (1) InterPro:IPR006820 (1) InterPro:IPR009057 (1) InterPro:IPR012287 (1) InterPro:IPR015705 (1) InterPro:IPR017970 (1) InterPro:IPR020479 (1)

PROSITE:PS00027 (1) PROSITE:PS50071 (1)

Pfam:PF00046 (1) Pfam:PF04731 (1)

Gene Product Description

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CONSTRUCTS WITH SEQUENCE FROM cdx4:

Tg(hsp70l:cdx4)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

cdx4 Contained in	[BAC] CH211-231B5 (1)    (order this) , CH211-276G21 (1)    (order this)
cdx4 Encodes	[BAC END] zk14a10.t7 [EST] cb546 (1)    (order this) , ibd1215 (1)    (order this) , ibd2812    (order this) , ibd5107 (1)    (order this) [cDNA] MGC:91785 (1)    (order this) , MGC:174156 (1)    (order this) , MGC:174157 (1)    (order this) , MGC:191602 (1)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131109 (1)	1587 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:AL935131 (1)	170938 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:Q90262 (1)	300 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:11836 (1)
All Sequence Information (22)

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OTHER  cdx4  GENE / MARKER PAGES:

Entrez Gene:798281 (1)

VEGA:OTTDARG00000021212 (1)

Ensembl(Zv8):ENSDARG00000036292 (1)

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MAPPING INFORMATION:

LG:  14 ,  5    Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	NT	CL	XH
Zebrafish	cdx4	14 ,  5
Human	CDX4	X (q13.2)	OMIM:300025 Entrez Gene:1046
Mouse	Cdx4	X (42.50 cM)	MGI:88362 Entrez Gene:12592
Orthology Details

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CITATIONS   (67)