ZFIN ID: ZDB-GENE-980526-283

Gene Name:early growth response 2b
Gene Symbol: egr2b

Previous Names: krx20, krox-20, egr2(1) , id:ibd5073(1) , cb427(1) , krox20, wu:fb71h10, zgc:92210
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	356 figure(s) from 247 publications
Directly submitted expression data:	6 figure(s) (15 images) from Thisse et al., 2001 [cb427]
	9 figure(s) (19 images) from Rauch et al., 2003 [fb71h10]
	2 figure(s) (2 images) from Kudoh et al., 2001 [ibd5073]
Wild Type Stages, Structures:	Cleavage:2-cell (0.75h-1.00h) to Larval:Days 7-13 (168.00h-14d, 4.5mm, 8 teeth)
	brain, cranial neural crest ... (all 22)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   5 genotypes
Allele(s):   fh227, unrec_egr2b

Phenotype: (current status)

Data:	2 figures from Monk et al., 2009
Observed in:	compact myelin, myelin sheath, posterior lateral line nerve

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	myelination of posterior lateral line nerve axons (more)
Cellular Component	intracellular (more)
Molecular Function	DNA binding (more)

All GO Terms (9)

Protein Families, Domains and Sites:

InterPro:IPR007087 (1) InterPro:IPR013087 (1) InterPro:IPR015880 (1) InterPro:IPR021849 (1)

PROSITE:PS00028 (1) PROSITE:PS50157 (1)

Pfam:PF00096 (1) Pfam:PF11928 (1)

Gene Product Description

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

egr2b Contained in	[BAC] DKEY-247F17 (1)    (order this)
egr2b Encodes	[EST] cb427 (1)    (order this) , fb71h10    (order this) , ibd5073 (1)    (order this) [cDNA] MGC:92210 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_130997 (1)	2065 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR354434 (1)	153813 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:Q05159 (1)	412 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:75080 (1)
All Sequence Information (14)

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OTHER  egr2b  GENE / MARKER PAGES:

Entrez Gene:30190 (1)

VEGA:OTTDARG00000027335 (1)

Ensembl(Zv8):ENSDARG00000042826 (1)

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MAPPING INFORMATION:

LG:  12  Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL
Zebrafish	egr2b	12
Human	EGR2	10 (q21.1)	OMIM:129010 Entrez Gene:1959
Mouse	Egr2	10 (35.00 cM)	MGI:95296 Entrez Gene:13654
Fruit fly	sr	3R	FLYBASE:FBgn0003499 Entrez Gene:42162
Orthology Details

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CITATIONS   (415)