Gene
asap1b
- ID
- ZDB-GENE-091112-16
- Name
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
- Symbol
- asap1b Nomenclature History
- Previous Names
-
- asap1
- si:dkey-37o8.2
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity. Predicted to be involved in positive regulation of GTPase activity. Orthologous to human ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Cui et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | AH/BAR domain superfamily | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | ArfGAP domain superfamily | ARFGAP/RecO-like zinc finger | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein | Arf GTPase activating protein | ASAP1, BAR domain | ASAP1, SH3 domain | ASAP, PH domain | BAR domain | PH-like domain superfamily | Pleckstrin homology domain | SH3 domain | SH3-like domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A2R8RMX4
|
1062 | |||||||||||||||
UniProtKB:A0A8M3ANG5
|
1133 | |||||||||||||||
UniProtKB:A0A8M3AZ08
|
1137 | |||||||||||||||
UniProtKB:A0A8M3AVY1
|
1136 | |||||||||||||||
UniProtKB:A0A8M2B9F9
|
1086 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
asap1b-201
(1)
|
Ensembl | 8,967 nt | ||
mRNA |
asap1b-202
(1)
|
Ensembl | 1,048 nt | ||
mRNA |
asap1b-204
(1)
|
Ensembl | 669 nt | ||
mRNA |
asap1b-205
(1)
|
Ensembl | 4,009 nt | ||
mRNA |
asap1b-206
(1)
|
Ensembl | 8,508 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-37O8 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_005162605 (1) | 5138 nt | ||
Genomic | GenBank:AL840641 (1) | 177428 nt | ||
Polypeptide | UniProtKB:A0A8M3AZ08 (1) | 1137 aa |
- Cui, J., Chen, G., Wen, D., Wang, Y., Zhao, Z., Wu, C. (2020) Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration. Frontiers in cellular and infection microbiology. 10:519503
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Ningappa, M., So, J., Glessner, J., Ashokkumar, C., Ranganathan, S., Min, J., Higgs, B.W., Sun, Q., Haberman, K., Schmitt, L., Vilarinho, S., Mistry, P.K., Vockley, G., Dhawan, A., Gittes, G.K., Hakonarson, H., Jaffe, R., Subramaniam, S., Shin, D., Sindhi, R. (2015) The Role of ARF6 in Biliary Atresia. PLoS One. 10:e0138381
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