Gene

aak1a

ID
ZDB-GENE-081105-101
Name
AP2 associated kinase 1a
Symbol
aak1a Nomenclature History
Previous Names
  • si:dkey-71c4.3 (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have AP-2 adaptor complex binding activity and protein serine/threonine kinase activity. Predicted to be involved in positive regulation of Notch signaling pathway; protein phosphorylation; and regulation of clathrin-dependent endocytosis. Predicted to localize to nucleus. Orthologous to human AAK1 (AP2 associated kinase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aak1a Human Ortholog
No data available
Associated With aak1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Family IPR051744 AP2-associated Ser/Thr protein kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length AP2-associated Ser/Thr protein kinase Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A0A8M2BES2 850
UniProtKB:A0A8M2BFD5 1052
UniProtKB:A0A8M2BER3 1051
UniProtKB:A0A8M2BEQ3 941
UniProtKB:A0A8N7TFM1 965
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA aak1a-201 (1) Ensembl 2,106 nt
mRNA aak1a-203 (1) Ensembl 2,550 nt
ncRNA aak1a-002 (1) Ensembl 534 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations