Gene
dis3
- ID
- ZDB-GENE-080213-3
- Name
- DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
- Symbol
- dis3 Nomenclature History
- Previous Names
-
- wu:fb08g12
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have 3'-5'-exoribonuclease activity and endonuclease activity. Predicted to be involved in rRNA catabolic process. Predicted to localize to cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Orthologous to human DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR022966 | Ribonuclease II/R, conserved site |
| Domain | IPR001900 | Ribonuclease II/R |
| Domain | IPR002716 | PIN domain |
| Domain | IPR033770 | Exosome complex exonuclease RRP44, S1 domain |
| Domain | IPR033771 | Rrp44-like cold shock domain |
| Domain | IPR041505 | Dis3-like cold-shock domain 2 |
| Family | IPR050180 | RNR Ribonuclease |
| Homologous_superfamily | IPR012340 | Nucleic acid-binding, OB-fold |
| Homologous_superfamily | IPR029060 | PIN-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Dis3-like cold-shock domain 2 | Exosome complex exonuclease RRP44, S1 domain | Nucleic acid-binding, OB-fold | PIN domain | PIN-like domain superfamily | Ribonuclease II/R | Ribonuclease II/R, conserved site | RNR Ribonuclease | Rrp44-like cold shock domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7FE01
|
950 |
Interactions and Pathways
No data available
Plasmids
No data available