Gene

foxj1a

ID

ZDB-GENE-060929-1178

Name

forkhead box J1a

Symbol

foxj1a Nomenclature History

Previous Names

foxj1 (1)
id:ibd5134
zgc:153050

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including central canal development; cerebrospinal fluid circulation; and embryonic heart tube morphogenesis. Predicted to be located in nucleus. Is expressed in several structures, including embryonic structure; mesoderm; nervous system; neural tube; and renal system. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 43. Orthologous to human FOXJ1 (forkhead box J1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

49 figures from 30 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 16 figures from 8 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With foxj1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
primary ciliary dyskinesia 43	Alliance	Ciliary dyskinesia, primary, 43	618699

Associated With foxj1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018122	Fork head domain conserved site1
Conserved_site	IPR030456	Fork head domain conserved site 2
Domain	IPR001766	Fork head domain
Domain	IPR047512	Forkhead box protein J1, forkhead domain
Family	IPR047513	Forkhead box protein J1
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Forkhead box protein J1	Forkhead box protein J1, forkhead domain	Fork head domain	Fork head domain conserved site1	Fork head domain conserved site 2	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:F1QDF8 InterPro	458

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	foxj1a-201 (1) Ensembl	Ensembl		4,564 nt	Select Tool ZFIN BLAST
mRNA	foxj1a-202 (1) Ensembl	Ensembl		4,231 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-foxj1	monoclonal	foxj1a	IgG1	Mouse	IHC WB	Abcam plc	2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations