ZFIN ID: ZDB-GENE-060929-1178
Gene Name: forkhead box J1a
Gene Symbol: foxj1a    Nomenclature History

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Previous Names: foxj1 (1), id:ibd5134, zgc:153050

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Exhibits sequence-specific DNA binding activity. Involved in several processes, including embryonic heart tube morphogenesis; epithelial cilium movement involved in extracellular fluid movement; and regulation of cilium beat frequency involved in ciliary motility. Predicted to localize to the nucleus. Is expressed in several structures, including mesoderm; nervous system; neural tube; renal system; and tail bud. Orthologous to human FOXJ1 (forkhead box J1).
Genome Resources: Alliance (1),  Gene:767737 (1),  Ensembl(GRCz11):ENSDARG00000101919 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
nw3 Insertion Unknown Unknown CRISPR
sa2090 Point Mutation Unknown Premature Stop ENU
sq5717 Small Deletion Unknown Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-foxj1a
1
CRISPR2-foxj1a
1
CRISPR3-foxj1a 1
CRISPR4-foxj1a 1
CRISPR5-foxj1a 1
MO1-foxj1a N/A 2
MO2-foxj1a N/A 4
MO3-foxj1a N/A 1
MO4-foxj1a N/A 1
MO5-foxj1a N/A 3
MO6-foxj1a N/A 3
DISEASE ASSOCIATED WITH foxj1a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ciliary dyskinesia, primary, 43 618699
DISEASE ASSOCIATED WITH foxj1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cilium assembly (more)
Cellular Component nucleus (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001766 Fork head domain
Conserved_site IPR018122 Fork head domain conserved site1
Conserved_site IPR030456 Fork head domain conserved site 2
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM foxj1a
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(foxj1a:EGFP) foxj1a EGFP Danio rerio 3 2
Tg(foxj1a:GFP) foxj1a GFP Danio rerio 2 8
tg(foxj1a:gfp,cryaa:gfp) cryaafoxj1a GFP Danio rerio 1 1
tg(foxj1a:icre,myl7:egfp) foxj1amyl7 CreEGFP Danio rerio 2 1
tg(foxj1a:mmu.arl13b-gfp,cryaa:gfp) cryaafoxj1a GFP Danio rerioMus musculus 1 1
Tg(foxj1a:ptk7a,cryaa:EGFP) cryaafoxj1a EGFPptk7a Danio rerio 4 2
Tg(hsp70l:foxj1a) hsp70l foxj1a Danio rerio 1 4
tg(xla.cryg:loxp-egfp,foxj1a:ptk7a-loxp-mcherry) foxj1a EGFPLOXPmCherryptk7a Danio rerioXenopus laevis 2 1
tg2(foxj1a:gfp) foxj1a GFP Danio rerio 1 1
MARKER RELATIONSHIPS
foxj1a Encodes: [EST] ibd5134 (1)
[cDNA] MGC:153050 (1), MGC:191713 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001076706 (1) 3786 bp
Genomic GenBank:CABZ01077367 (1) 32294 bp
Select Tool
Polypeptide UniProtKB:F1QDF8 (1) 458 aa
Sequence Information (all 20)
ORTHOLOGY for foxj1a ( Chr: 3 )
CITATIONS (74)