Gene

foxj1a

ID
ZDB-GENE-060929-1178
Name
forkhead box J1a
Symbol
foxj1a Nomenclature History
Previous Names
  • foxj1 (1)
  • id:ibd5134
  • zgc:153050
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits sequence-specific DNA binding activity. Involved in several processes, including embryonic heart tube morphogenesis; epithelial cilium movement involved in extracellular fluid movement; and regulation of cilium beat frequency involved in ciliary motility. Predicted to localize to nucleus. Is expressed in several structures, including mesoderm; nervous system; neural tube; renal system; and tail bud. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 43. Orthologous to human FOXJ1 (forkhead box J1).
Genome Resources
Note
None
Expression
All Expression Data
40 figures from 25 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With foxj1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ciliary dyskinesia 43 Alliance Ciliary dyskinesia, primary, 43 618699
Associated With foxj1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018122 Fork head domain conserved site1
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Fork head domain Fork head domain conserved site1 Fork head domain conserved site 2 Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:F1QDF8 458
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-foxj1 monoclonal IgG1 Mouse
  • IHC
  • WB
Abcam plc
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations