PUBLICATION

Isolation and expression analysis of foxj1 and foxj1.2 in zebrafish embryos

Authors
Aamar, E., and Dawid, I.B.
ID
ZDB-PUB-081031-4
Date
2008
Source
The International journal of developmental biology   52(7): 985-991 (Journal)
Registered Authors
Aamar, Emil, Dawid, Igor B.
Keywords
none
MeSH Terms
  • Amino Acid Sequence
  • Animals
  • Cilia/metabolism
  • Embryo, Nonmammalian
  • Forkhead Transcription Factors/genetics*
  • Forkhead Transcription Factors/metabolism
  • Gene Expression*
  • In Situ Hybridization
  • Left-Right Determination Factors
  • Molecular Sequence Data
  • Phylogeny
  • Sequence Homology, Amino Acid
  • Zebrafish/embryology*
  • Zebrafish/genetics*
  • Zebrafish/metabolism
  • Zebrafish Proteins/genetics*
  • Zebrafish Proteins/metabolism
PubMed
18956329 Full text @ Int. J. Dev. Biol.
Abstract
In this report, we present the isolation and identification of a zebrafish homolog of the winged helix\forkhead transcription factor Foxj1. Foxj1 was identified in other species but not in zebrafish. Foxj1 was shown in mice to be required in ciliogenesis and left-right asymmetry establishment. Here we present a spatio-temporal expression pattern of zebrafish foxj1, showing that this gene is expressed in dorsal forerunner cells, Kupffers vesicle, the floor plate, pronephric ducts and kidney. This expression pattern is overlapping but different from that of the foxj1.2, the closest related gene in zebrafish. Foxj1 in zebrafish appears to have similar functions as those reported in other species connected to ciliogenesis and left-right asymmetry.
Genes / Markers
Figures
Figure Gallery
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes