Isolation and expression analysis of foxj1 and foxj1.2 in zebrafish embryos
- Aamar, E., and Dawid, I.B.
- The International journal of developmental biology 52(7): 985-991 (Journal)
- Registered Authors
- Aamar, Emil, Dawid, Igor B.
- MeSH Terms
- Amino Acid Sequence
- Embryo, Nonmammalian
- Forkhead Transcription Factors/genetics*
- Forkhead Transcription Factors/metabolism
- Gene Expression*
- In Situ Hybridization
- Left-Right Determination Factors
- Molecular Sequence Data
- Sequence Homology, Amino Acid
- Zebrafish Proteins/genetics*
- Zebrafish Proteins/metabolism
- 18956329 Full text @ Int. J. Dev. Biol.
Aamar, E., and Dawid, I.B. (2008) Isolation and expression analysis of foxj1 and foxj1.2 in zebrafish embryos. The International journal of developmental biology. 52(7):985-991.
In this report, we present the isolation and identification of a zebrafish homolog of the winged helix\forkhead transcription factor Foxj1. Foxj1 was identified in other species but not in zebrafish. Foxj1 was shown in mice to be required in ciliogenesis and left-right asymmetry establishment. Here we present a spatio-temporal expression pattern of zebrafish foxj1, showing that this gene is expressed in dorsal forerunner cells, Kupffers vesicle, the floor plate, pronephric ducts and kidney. This expression pattern is overlapping but different from that of the foxj1.2, the closest related gene in zebrafish. Foxj1 in zebrafish appears to have similar functions as those reported in other species connected to ciliogenesis and left-right asymmetry.
Genes / Markers
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Engineered Foreign Genes
Errata and Notes