Gene

fbxo44.5

ID

ZDB-GENE-040801-53

Name

F-box protein 44, tandem duplicate 5

Symbol

fbxo44.5 Nomenclature History

Previous Names

zgc:100832

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; glycoprotein catabolic process; and ubiquitin-dependent ERAD pathway. Predicted to localize to SCF ubiquitin ligase complex and cytoplasm. Orthologous to several human genes including FBXO44 (F-box protein 44).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fbxo44.5 Human Ortholog

No data available

Associated With fbxo44.5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001810	F-box domain
Domain	IPR007397	F-box associated (FBA) domain
Family	IPR039752	F-box only protein
Homologous_superfamily	IPR008979	Galactose-binding-like domain superfamily
Homologous_superfamily	IPR036047	F-box-like domain superfamily

Domain Details Per Protein

Protein	Length	F-box associated (FBA) domain	F-box domain	F-box-like domain superfamily	F-box only protein	Galactose-binding-like domain superfamily
UniProtKB:A0A0R4IQM2 InterPro	276
UniProtKB:Q6DEK8 InterPro	247
UniProtKB:F1Q8M7 InterPro	247

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	zgc:100832-201 (1) Ensembl	Ensembl	722 nt	Select Tool
mRNA	zgc:100832-202 (1) Ensembl	Ensembl	1,960 nt	Select Tool
mRNA	zgc:100832-203 (1) Ensembl	Ensembl	3,084 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl
Note: This gene is in a cluster of ten fbxo6/fbxo44 genes and relationships are difficult to discern. Current analysis (January 2021) suggests three fbxo44 and fbxo6 gene pairs followed by four additional fbxo44 genes.

Citations