Research
General Information
ZIRC
ZFIN: Gene: hdac3
ZFIN ID: ZDB-GENE-040426-847

Gene Name:histone deacetylase 3
Gene Symbol: hdac3
Previous Names: zgc:55927(1)
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 9 figure(s) from 3 publications
Directly submitted expression data: 7 figure(s) (7 images) from Thisse et al., 2008 [MGC:55927]
  1 figure(s) (1 images) from Thisse et al., 2004 [MGC:55927]
Wild Type Stages, Structures: Zygote:1-cell (0.00h-0.75h) to Larval:Day 5 (120.00h-144.00h, 3.9mm, 6 teeth)
  unspecified, whole organism
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   2 genotypes
Allele(s):   hi2786aTg
Phenotype: (current status)
  Data: 5 figures from 2 publications
  Observed in: intersegmental vessel, liver, liver development, whole organism
Knockdown reagents: MO1-hdac3 (1) ,   MO2-hdac3 (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process angiogenesis (more)
Cellular Component nucleus
Molecular Function histone deacetylase activity (more)
All GO Terms (9)

Protein Families, Domains and Sites:
  • InterPro:IPR000286 (1)
  • InterPro:IPR003084 (1)
  • Pfam:PF00850 (1)
  • EC:3.5.1.98 (1)
  • Loading Transcript Data...

    Gene Product Description


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    hdac3 Contained in [BAC] CH211-194M19 (1)    (order this)
    hdac3 Encodes [cDNA] MGC:55927 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200990 (1) 2069 bp
    Genomic GenBank:BX927254 (1) 152687 bp
    Polypeptide UniProtKB:Q803C3 (1) 428 aa
    Sequence Clusters UniGene:80607 (1)
    All Sequence Information (7)

    OTHER  hdac3  GENE / MARKER PAGES:

  • Entrez Gene:393965 (1)
  • VEGA:OTTDARG00000027868 (1)
  • Ensembl(Zv8):ENSDARG00000037514 (1)

  • MAPPING INFORMATION:
      LG:  14  Details

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish hdac3  14
    Human HDAC3  5 (q31)
  • OMIM:605166
  • Entrez Gene:8841
  • Orthology Details

    CITATIONS   (15)