ZFIN ID: ZDB-GENE-010803-2

Gene Name:sprouty (Drosophila) homolog 4
Gene Symbol: spry4

Previous Names: zSpry4(1) , wu:fb92b06(1) , sprouty4(1) , cb511(1)
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	31 figure(s) from 23 publications
Directly submitted expression data:	7 figure(s) (49 images) from Thisse et al., 2001 [cb511]
Wild Type Stages, Structures:	Blastula:Sphere (4.00h-4.33h) to Adult (90d-730d, breeding adult)
	central nervous system, diencephalon ... (all 44)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   3 genotypes
Allele(s):   fh117, unrec_spry4

Phenotype: (current status)

Knockdown reagents: MO1-spry4 (1) ,   MO2-spry4 (1) ,   MO3-spry4 (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	hemopoiesis (more)
Cellular Component	membrane
Molecular Function	molecular_function

All GO Terms (6)

Protein Families, Domains and Sites:

InterPro:IPR007875 (1)

PROSITE:PS51227 (1)

Pfam:PF05210 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

spry4 Contains	[SNP] rs3729148 (1) , rs3729149 (1) , rs3729150 (1)
spry4 Encodes	[EST] cb511 (2)    (order this) , fb92b06 (1) , fc35e06 (1) [cDNA] MGC:92545 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131826 (1)	2890 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Polypeptide	UniProtKB:Q90XH4 (1)	310 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:32057 (1)
All Sequence Information (11)

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OTHER  spry4  GENE / MARKER PAGES:

Entrez Gene:114437 (1)

Ensembl(Zv8):ENSDARG00000068732 (1)

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MAPPING INFORMATION:

LG:  16 ,  21  Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA
Zebrafish	spry4	16 ,  21
Human	SPRY4	5 (q31.3)	OMIM:607984 Entrez Gene:81848
Mouse	Spry4	18 (18.00 cM)	MGI:1345144 Entrez Gene:24066
Orthology Details

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CITATIONS   (59)