Research
General Information
ZIRC
ZFIN ID: ZDB-LAB-991005-53
Zebrafish International Resource Center (ZIRC)
5274 University of Oregon
Eugene, OR
97403-5274
USA
Contact Info:
Contact Person: Quinn, Erin
Phone: (541) 346-6028 x10
Fax: (541) 346-6151
Email: zirc@zebrafish.org
URL: http://zebrafish.org/
Line Designation: rc 		Lab Members:
Varga, Zoltan M. , PI/Director
Westerfield, Monte , PI/Director
Kent, Michael , Co-PI/Senior Scientist
Murray, Katy , MD/Veterinarian
Hwang-Shum, Jen-Jen , Research Staff
Nasiadka, Andrzej , Research Staff
Bailey, Austin , Fish Facility Staff
Bauer, Justin , Fish Facility Staff
Carmichael, Carrie , Fish Facility Staff
Clark, Renee , Fish Facility Staff

Lains, David , Fish Facility Staff
Miller, Chapell , Fish Facility Staff
Smith, Calvin , Fish Facility Staff
Van Gordon, Andrew , Fish Facility Staff
Williams, Evan , Fish Facility Staff
Botvinnik, Irina , Technical Staff
Hennesy, Gordon , Technical Staff
Holland, Ron , Technical Staff
McCarthy, Bruce , Technical Staff
Freeman, April , Administrative Staff
Quinn, Erin , Administrative Staff
Statement of Research Interests:

The Zebrafish International Resource Center provides a central repository for wild-type and mutant strains of zebrafish (Danio rerio) and for materials and information about zebrafish research. Materials and zebrafish strains are collected from and distributed to the research community.

Obtain stocks, cDNAs, ESTs or other materials on-line form
Submit stocks using our on-line form
Pathology services on-line form
Husbandry services on-line form

Standards and procedures for maintaining healthy strains of zebrafish are being developed and a manual for prevention, diagnosis, and treatment of diseases affecting zebrafish is being prepared.

Zebrafish Publications of Lab members :
Dahdul, W.M., Balhoff, J.P., Engeman, J., Grande, T., Hilton, E.J., Kothari, C., Lapp, H., Lundberg, J.G., Midford, P.E., Vision, T.J., Westerfield, M., and Mabee, P.M. (2010) Evolutionary characters, phenotypes and ontologies: curating data from the systematic biology literature. PLoS One. 5(5):e10708
Dahdul, W.M., Lundberg, J.G., Midford, P.E., Balhoff, J.P., Lapp, H., Vision, T.J., Haendel, M.A., Westerfield, M., and Mabee, P.M. (2010) The teleost anatomy ontology: anatomical representation for the genomics age. Syst. Biol.. 59(4):369-383
Delaurier, A., Eames, B.F., Blanco-Sánchez, B., Peng, G., He, X., Swartz, M.E., Ullmann, B., Westerfield, M., and Kimmel, C.B. (2010) Zebrafish sp7:EGFP: A transgenic for studying otic vesicle formation, skeletogenesis, and bone regeneration. Genesis. 48(8):505-511
Ebermann, I., Phillips, J.B., Liebau, M.C., Koenekoop, R.K., Schermer, B., Lopez, I., Schäfer, E., Roux, A.F., Dafinger, C., Bernd, A., Zrenner, E., Claustres, M., Blanco, B., Nürnberg, G., Nürnberg, P., Ruland, R., Westerfield, M., Benzing, T., and Bolz, H.J. (2010) PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome. J. Clin. Invest.. 120(6):1812-1823
Carmichael, C., Westerfield, M., and Varga, Z.M. (2009) Cryopreservation and in vitro fertilization at the zebrafish international resource center. Methods Mol. Biol.. 546:45-65
Hagedorn, M., Ricker, J., McCarthy, M., Meyers, S.A., Tiersch, T.R., Varga, Z.M., and Kleinhans, F.W. (2009) Biophysics of zebrafish (Danio rerio) sperm. Cryobiology. 58(1):12-19
Lawrence, C., Sanders, G.E., Varga, Z.M., Baumann, D.P., Freeman, A., Baur, B., and Francis, M. (2009) Regulatory Compliance and the Zebrafish. Zebrafish. 6(4):453-456
Ochi, H., and Westerfield, M. (2009) Lbx2 regulates formation of myofibrils. BMC Dev. Biol.. 9:13
Ramsay, J.M., Feist, G.W., Varga, Z.M., Westerfield, M., Kent, M.L., and Schreck, C.B. (2009) Whole-body cortisol response of zebrafish to acute net handling stress. Aquaculture. 297(1-4):157-162
Ramsay, J.M., Watral, V., Schreck, C.B., and Kent, M.L. (2009) Pseudoloma neurophilia infections in zebrafish Danio rerio: effects of stress on survival, growth, and reproduction. Dis. Aquat. Organ.. 88(1):69-84
Toro, S., Wegner, J., Muller, M., Westerfield, M., and Varga, Z.M. (2009) Identification of differentially expressed genes in the zebrafish hypothalamic-pituitary axis. Gene Expr. Patterns. 9(4):200-208
Viktorin, G., Chiuchitu, C., Rissler, M., Varga, Z.M., and Westerfield, M. (2009) Emx3 is required for the differentiation of dorsal telencephalic neurons. Dev. Dyn.. 238(8):1984-1998
Washington, N.L., Haendel, M.A., Mungall, C.J., Ashburner, M., Westerfield, M., and Lewis, S.E. (2009) Linking Human Diseases to Animal Models Using Ontology-Based Phenotype Annotation. PLoS Biol.. 7(11):e1000247
Dutta, S., Dietrich, J.E., Westerfield, M., and Varga, Z.M. (2008) Notch signaling regulates endocrine cell specification in the zebrafish anterior pituitary. Dev. Biol.. 319(2):248-257
Ochi, H., Hans, S., and Westerfield, M. (2008) Smarcd3 regulates the timing of zebrafish myogenesis onset. J. Biol. Chem.. 283(6):3529-3536
Ostland, V.E., Watral, V., Whipps, C.M., Austin, F.W., St-Hilaire, S., Westerman, M.E., and Kent, M.L. (2008) Biochemical, molecular, and virulence characteristics of select Mycobacterium marinum isolates in hybrid striped bass Morone chrysops x M. saxatilis and zebrafish Danio rerio. Dis. Aquat. Organ.. 79(2):107-118
Rotllant, J., Liu, D., Yan, Y.L., Postlethwait, J.H., Westerfield, M., and Du, S.J. (2008) Sparc (Osteonectin) functions in morphogenesis of the pharyngeal skeleton and inner ear. Matrix Biol.. 27(6):561-572
Sprague, J., Bayraktaroglu, L., Bradford, Y., Conlin, T., Dunn, N., Fashena, D., Frazer, K., Haendel, M., Howe, D.G., Knight, J., Mani, P., Moxon, S.A., Pich, C., Ramachandran, S., Schaper, K., Segerdell, E., Shao, X., Singer, A., Song, P., Sprunger, B., Van Slyke, C.E., and Westerfield, M. (2008) The Zebrafish Information Network: the zebrafish model organism database provides expanded support for genotypes and phenotypes. Nucleic Acids Res.. 36:D768-772
Whipps, C.M., Matthews, J.L., and Kent, M.L. (2008) Distribution and genetic characterization of Mycobacterium chelonae in laboratory zebrafish Danio rerio. Dis. Aquat. Organ.. 82(1):45-54
Baden, K.N., Murray, J., Capaldi, R.A., and Guillemin, K. (2007) Early developmental pathology due to cytochrome c oxidase deficiency is revealed by a new zebrafish model. J. Biol. Chem.. 282(48):34839-34849
Chen, Y.H., Wang, Y.H., Chang, M.Y., Lin, C.Y., Weng, C.W., Westerfield, M., and Tsai, H.J. (2007) Multiple upstream modules regulate zebrafish myf5 expression. BMC Dev. Biol.. 7(1):1
Hans, S., and Westerfield, M. (2007) Changes in retinoic acid signaling alter otic patterning. Development. 134(13):2449-2458
Hans, S., Christison, J., Liu, D., and Westerfield, M. (2007) Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b. BMC Dev. Biol.. 7(1):5
Mabee, P.M., Arratia, G., Coburn, M., Haendel, M., Hilton, E.J., Lundberg, J.G., Mayden, R.L., Rios, N., and Westerfield, M. (2007) Connecting evolutionary morphology to genomics using ontologies: a case study from Cypriniformes including zebrafish. J. Exp. Zoolog. B Mol. Dev. Evol.. 308(5):655-668
Mabee, P.M., Ashburner, M., Cronk, Q., Gkoutos, G.V., Haendel, M., Segerdell, E., Mungall, C., and Westerfield, M. (2007) Phenotype ontologies: the bridge between genomics and evolution. Trends Ecol. Evol.. 22(7):345-350
Nixon, S.J., Carter, A., Wegner, J., Ferguson, C., Floetenmeyer, M., Riches, J., Key, B., Westerfield, M., and Parton, R.G. (2007) Caveolin-1 is required for lateral line neuromast and notochord development. J. Cell Sci.. 120(13):2151-2161
Ochi, H., and Westerfield, M. (2007) Signaling networks that regulate muscle development: lessons from zebrafish. Dev. Growth Differ.. 49(1):1-11
Schlueter, P.J., Peng, G., Westerfield, M., and Duan, C. (2007) Insulin-like growth factor signaling regulates zebrafish embryonic growth and development by promoting cell survival and cell cycle progression. Cell Death Differ.. 14(6):1095-1105
Toro, S., and Varga, Z.M. (2007) Equivalent progenitor cells in the zebrafish anterior preplacodal field give rise to adenohypophysis, lens, and olfactory placodes. Semin. Cell Dev. Biol.. 18(4):534-542
Watral, V., and Kent, M.L. (2007) Pathogenesis of Mycobacterium spp. in zebrafish (Danio rerio) from research facilities. Comp. Biochem. Physiol. C Toxicol. Pharmacol.. 145(1):55-60
Whipps, C.M., Dougan, S.T., and Kent, M.L. (2007) Mycobacterium haemophilum infections of zebrafish (Danio rerio) in research facilities. FEMS Microbiol. Lett.. 270(1):21-26
Yang, H., Carmichael, C., Varga, Z.M., and Tiersch, T.R. (2007) Development of a simplified and standardized protocol with potential for high-throughput for sperm cryopreservation in zebrafish Danio rerio. Theriogenology. 68(2):128-136
Bates, J.M., Mittge, E., Kuhlman, J., Baden, K.N., Cheesman, S.E., and Guillemin, K. (2006) Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation. Dev. Biol.. 297(2):374-386
Ochi, H., Pearson, B.J., Chuang, P.T., Hammerschmidt, M., and Westerfield, M. (2006) Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened. Dev. Biol.. 297(1):127-140
Peng, G., and Westerfield, M. (2006) Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists. Development. 133(16):3191-3200
Ramsay, J.M., Feist, G.W., Varga, Z.M., Westerfield, M., Kent, M.L., and Schreck, C.B. (2006) Whole-body cortisol is an indicator of crowding stress in adult zebrafish, Danio rerio. Aquaculture. 258(1-4):565-574
Seth, A., Culverwell, J., Walkowicz, M., Toro, S., Rick, J.M., Neuhauss, S.C., Varga, Z.M., and Karlstrom, R.O. (2006) belladonna/(lhx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain. Development. 133(4):725-735
Sprague, J., Bayraktaroglu, L., Clements, D., Conlin, T., Fashena, D., Frazer, K., Haendel, M., Howe, D.G., Mani, P., Ramachandran, S., Schaper, K., Segerdell, E., Song, P., Sprunger, B., Taylor, S., Van Slyke, C.E., and Westerfield, M. (2006) The Zebrafish Information Network: the zebrafish model organism database. Nucleic Acids Res.. 34:D581-585
Dutta, S., Dietrich, J.E., Aspock, G., Burdine, R.D., Schier, A., Westerfield, M., and Varga, Z.M. (2005) pitx3 defines an equivalence domain for lens and anterior pituitary placode. Development. 132(7):1579-1590
Nixon, S.J., Wegner, J., Ferguson, C., Méry, P.F., Hancock, J.F., Currie, P.D., Key, B., Westerfield, M., and Parton, R.G. (2005) Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterning. Hum. Mol. Genet.. 14(13):1727-1743
Wang-Buhler, J.L., Lee, S.J., Chung, W.G., Stevens, J.F., Tseng, H.P., Hseu, T.H., Hu, C.H., Westerfield, M., Yang, Y.H., Miranda, C.L., and Buhler, D.R. (2005) CYP2K6 from zebrafish (Danio rerio): Cloning, mapping, developmental/tissue expression, and aflatoxin B1 activation by baculovirus expressed enzyme. Comp. Biochem. Physiol. C Toxicol. Pharmacol.. 140(2):207-219
Yan, Y.L., Willoughby, J., Liu, D., Crump, J.G., Wilson, C., Miller, C.T., Singer, A., Kimmel, C., Westerfield, M., and Postlethwait, J.H. (2005) A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development. Development. 132(5):1069-1083
Hans, S., Liu, D., and Westerfield, M. (2004) Pax8 and Pax2a function synergistically in otic specification, downstream of the Foxi1 and Dlx3b transcription factors. Development. 131(20):5091-5102
Henrich, T., Ramialison, M., Segerdell, E., Westerfield, M., Furutani-Seiki, M., Wittbrodt, J., Kondoh, H. (2004) GSD: a genetic screen database. Mech. Dev.. 121(7-8):959-963
Herzog, W., Sonntag, C., Von Der Hardt, S., Roehl, H.H., Varga, Z.M., and Hammerschmidt, M. (2004) Fgf3 signaling from the ventral diencephalon is required for early specification and subsequent survival of the zebrafish adenohypophysis. Development. 131(15):3681-3692
Hirsinger, E., Stellabotte, F., Devoto, S.H., and Westerfield, M. (2004) Hedgehog signaling is required for commitment but not initial induction of slow muscle precursors. Dev. Biol.. 275(1):143-157
Jensen, A.M., and Westerfield, M. (2004) Zebrafish Mosaic Eyes Is a Novel FERM Protein Required for Retinal Lamination and Retinal Pigmented Epithelial Tight Junction Formation. Curr. Biol.. 14(8):711-717
Kent, M.L., Whipps, C.M., Matthews, J.L., Florio, D., Watral, V., Bishop-Stewart, J.K., Poort, M., and Bermudez, L. (2004) Mycobacteriosis in zebrafish (Danio rerio) research facilities. Comp. Biochem. Physiol. C Toxicol. Pharmacol.. 138(3):383-390
Wiellette, E., Grinblat, Y., Austen, M., Hirsinger, E., Amsterdam, A., Walker, C., Westerfield, M., and Sive, H. (2004) Combined haploid and insertional mutation screen in the zebrafish. Genesis. 40(4):231-240
Kent, M.L. and Bishop-Stewart, J.K. (2003) Transmission and tissue distribution of Pseudoloma neurophilia (Microsporidia) of zebrafish, Danio rerio (Hamilton). J. Fish Dis.. 26(7):423-426
Liu, D., Chu, H., Maves, L., Yan, Y.-L., Morcos, P.A., Postlethwait, J.H., and Westerfield, M. (2003) Fgf3 and Fgf8 dependent and independent transcription factors are required for otic placode specification. Development. 130(10):2213-2224
Spitsbergen, J.M. and Kent, M.L. (2003) The state of the art of the zebrafish model for toxicology and toxicologic pathology research--advantages and current limitations. Toxicol. Pathol.. (Suppl.) 31:62-87
Spitsbergen, J.M., and Kent, M.L. (2003) The State of the Art of the Zebrafish Model for Toxicology and Toxicologic Pathology Research--Advantages and Current Limitations. Toxicol. Pathol.. (Suppl.) 31:62-87
Sprague, J., Clements, D., Conlin, T., Edwards, P., Frazer, K., Schaper, K., Segerdell, E., Song, P., Sprunger, B., and Westerfield, M. (2003) The Zebrafish Information Network (ZFIN): the zebrafish model organism database. Nucleic Acids Res.. 31(1):241-243
Kent, M.L., Bishop-Stewart, J.K., Matthews, J.L., and Spitsbergen, J.M. (2002) Pseudocapillaria tomentosa, a nematode pathogen, and associated neoplasms of zebrafish (Danio rerio) kept in research colonies. Comp. Med.. 52(4):354-358
Yan, Y.-L., Miller, C.T., Nissen, R.M., Singer, A., Liu, D., Kirn, A., Draper, B., Willoughby, J., Morcos, P.A., Amsterdam, A., Chung, B.-C., Westerfield, M., Haffter, P., Hopkins, N., Kimmel, C., and Postlethwait, J.H. (2002) A zebrafish sox9 gene required for cartilage morphogenesis. Development. 129(21):5065-5079
Hawkins, W.E., Clark, M.S., Shima, A., Walter, R.B., Winn, R.N., and Westerfield, M. (2001) Four resource centers for fishes: specifies, stocks, and services. Mar. Biotechnol.. 3:S239-S248
Hirsinger, E. and Westerfield, M. (2001) Segregation of zebrafish muscle lineages: lineage relationships and cellular commitment. Dev. Biol.. 235(1):180 (#40)
Jensen, A.M. and Westerfield, M. (2001) Zebrafish mosaic eyes gene is required for tight junction formation in the retinal pigmented epithelium. Dev. Biol.. 235(1):181 (#46)
Jensen, A.M., Walker, C., and Westerfield, M. (2001) mosaic eyes: a zebrafish gene required in pigmented epithelium for apical localization of retinal cell division and lamination. Development. 128(1):95-105
Matthews, J.L., Brown, A.M.V., Larison, K., Bishop-Stewart, J.K., Rogers, P., and Kent, M.L. (2001) Pseudoloma neurophilia n. g., n. sp., a new microsporidium from the central nervous system of the zebrafish (Danio rerio). J. Eukaryot. Microbiol.. 48(2):227-233
Rohr, K.B., Barth, K.A., Varga, Z.M., and Wilson, S.W. (2001) The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity. Neuron. 29(2):341-351
Sprague, J., Doerry, E., Douglas, S., Westerfield, M., and ZFIN GRP, (Conlin, T., Clements, D., Edwards, P., Frazer, K., Schaper, K., Segerdell, E.) (2001) The Zebrafish Information Network (ZFIN): a resource for genetic, genomic and developmental research. Nucleic Acids Res.. 29(1):87-90
Varga, Z.M., Amores, A., Lewis, K.E., Yan, Y.-L., Postlethwait, J.H., Eisen, J.S., and Westerfield, M. (2001) Zebrafish smoothened functions in ventral neural tube specification and axon tract formation. Development. 128(18):3497-3509
De Martino, S., Yan, Y.-L., Jowett, T., Postlethwait, J.H., Varga, Z.M., Ashworth, A., and Austin, C.A. (2000) Expression of sox11 gene duplicates in zebrafish suggests the reciprocal loss of ancestral gene expression patterns in development. Dev. Dyn.. 217(3):279-292
Whitlock, K.E. and Westerfield, M. (2000) The olfactory placodes of the zebrafish form by convergence of cellular fields at the edge of the neural plate. Development. 127(17):3645-3653
Appel, B., Fritz, A., Westerfield, M., Grunwald, D.J., Eisen, J.S., and Riley, B.B. (1999) Delta-mediated specification of midline cell fates in zebrafish embryos. Curr. Biol.. 9:247-256
Detrich, H.W. III, Westerfield, M., and Zon, L.I. (1999) Overview of the zebrafish system. In The Zebrafish: Biology. H.W. Detrich, L.I. Zon, and M. Westerfield, eds. Methods Cell Biol.. 59:3-10
Detrich, H.W. III, Westerfield, M., and Zon, L.I., eds. (1999) The Zebrafish: Biology. San Diego: Academic Press, Methods Cell Biol.. 59:391
Detrich, H.W. III, Westerfield, M., and Zon, L.I., eds. (1999) The Zebrafish: Genetics and Genomics. San Diego: Academic Press. 60:407
Fashena, D. and Westerfield, M. (1999) Secondary motoneuron axons localize DM-GRASP on their fasciculated segments. J. Comp. Neurol.. 406(3):415-424
Varga, Z.M., Wegner, J., and Westerfield, M. (1999) Anterior movement of ventral diencephalic precursors separates the primordial eye field in the neural plate and requires cyclops. Development. 126:5533-5546
Westerfield, M., Doerry, E., and Douglas, S. (1999) Zebrafish in the net. Trends Genet.. 15(6):248-249
Westerfield, M., Doerry, E., Kirkpatrick, A.E., and Douglas, S.A. (1999) Zebrafish informatics and the ZFIN database. In The Zebrafish: Genetics and Genomics, H.W. Detrich, III, M. Westerfield, and L.I. Zon, eds., San Diego, CA: Academic Press, Methods Cell Biol.. 60:339-355
Amores, A., Force, A., Yan, Y.-L. Joly, L., Amemiya, C., Fritz, A., Ho, R., Langeland, J., Prince, V., Wang, Y.-L., Westerfield, M., Ekker, M., and Postlethwait, J.H. (1998) Zebrafish hox clusters and vertebrate genome evolution. Science.. 282:1711-1714
Doerry, E., Douglas, S.A., Kirkpatrick, A.E., and Westerfield, M. (1998) The zebrafish information network project. Interactions. 3:69
Houart, C., M. Westerfield, and S.W. Wilson (1998) A small population of anterior cells patterns the forebrain during gastrulation. Nature. 391:788-792
Postlethwait, J.H, Yan, Y.-L., Gates, M.A., Horne, S., Amores, A., Brownlie, A., Donovan, A., Egan, E.S., Force, A., Gong, Z., Goutel, C., Fritz, A., Kelsh, R., Knapik, E., Liao, E., Paw, B., Ransom, D., Singer, A., Thomson, M., Abduljabbar, T.S., Yelick, P., Beier, D., Joly, J.-S., Larhammar, D., Rosa, F., Westerfield, M., Zon, L.I., Johnson, S.L., and Talbot, W.S. (1998) Vertebrate genome evolution and the zebrafish gene map. Nature Genet.. 18:345-349
Sepich, D.S., Wegner, J., O'Shea, S., and Westerfield, M. (1998) An altered intron inhibits synthesis of the acetylcholine receptor alpha-subunit in the paralyzed zebrafish mutant nic1. Genetics. 184:361-372
Whitlock, K.E. and Westerfield, M. (1998) A transient population of neurons pioneers the olfactory pathway in the zebrafish. J. Neurosci.. 18:8919-8927
Doerry, E., Douglas, S., Kirkpatrick, T., and Westerfield, M. (1997) Moving beyond html to create a multimedia database with user-centered design: a case study of a biological database. Tech. Report CIS-TR-97-02, Computer and Information Science Department, University of Oregon.
Doerry, E., Douglas, S.A., Kirkpatrick, A.E., and Westerfield, M. (1997) Participatory design for widely-distributed scientific communities. Proc. 3rd Conf. Human Factors and the Web.
Doerry, E., Kirkpatrick, A.E., Douglas, S.A., and Westerfield, M. (1997) Task-centered Navigation in a Web-accessible Data Space. AACE/WebNet97 conference on WWW, Internet, and Intranet, Toronto, Canada, Nov. 1,1997.
Du, S.J., S.H. Devoto, M. Westerfield, and R.T. Moon (1997) Positive and negative regulation of muscle cell identity by members of the hedgehog and TGF-b gene families. J. Cell Biol.. 139:145-156
Ekker, M., Akimenko, M.-A., Allende, M.L., Smith, R., Drouin, G., Langille, R.M., Weinberg, E.S., and Westerfield, M. (1997) Relationships among msx gene structure and function in zebrafish and other vertebrates. Mol. Biol. Evol.. 14:1008-1022
Fishman, M., D.Y. Stainier, R. Breitbart, and M. Westerfield (1997) Zebrafish: Genetic and embryological methods in a transparent vertebrate embryo. Methods Cell Biol.. 52:67-82
Melançon, E., Liu, D.W.C., Westerfield, M., and Eisen, J.S. (1997) Pathfinding by identified zebrafish motoneurons in the absence of muscle pioneers. J. Neurosci.. 17(20):7796-7804
Westerfield, M., E. Doerry, A.E. Kirkpatrick, W. Driever, and S.A. Douglas (1997) An on-line database for zebrafish development and genetics research. Sem. Cell Dev. Biol.. 8:477-488
Devoto, S.H., Melancon, E., Amacher, S.L., Eisen, J.S., and Westerfield, M. (1996) Influence of axial mesoderm on the development of slow muscle precursors. Dev. Biol.. 175(2):386
Devoto, S.H., Melancon, E., Eisen, J.S., and Westerfield, M. (1996) Identification of separate slow and fast muscle precursor cells in vivo, prior to somite formation. Development. 122(11):3371-3380
Fritz, A., Rozowski, M., Walker, C., and Westerfield, M. (1996) Identification of selected gamma-ray induced deficiencies in zebrafish using multiplex polymerase chain reaction. Genetics. 144(4):1735-1745
Akimenko, M.A., Johnson, S.L., Westerfield, M., and Ekker, M. (1995) Differential induction of four msx homeobox genes during fin development and regeneration in zebrafish. Development. 121:347-357
Westerfield, M. (1995) The Zebrafish Book. A Guide for the Laboratory Use of Zebrafish (Danio rerio), 3rd Edition. Eugene, OR, University of Oregon Press,. 385
Akimenko, M.A., Ekker, M., Wegner, J., Lin, W., and Westerfield, M. (1994) Combinatorial expression of three zebrafish genes related to distal-less: part of a homeobox gene code for the head. J. Neurosci.. 14:3475-3486
Reinhard, E., Nedivi, E., Wegner, J., Skene, J.H.P., and Westerfield, M. (1994) Neural selective activation and temporal regulation of a mammalian GAP-43 promoter in zebrafish. Development. 120:1767-1775
Sepich, D.S., Ho, R.K., and Westerfield, M. (1994) Autonomous expression of the nic1 acetylcholine receptor mutation in zebrafish muscle cells. Dev. Biol.. 161:84-90
Westerfield, M. (1993) The Zebrafish Book; A Guide for the Laboratory Use of Zebrafish (Brachydanio rerio). University of Oregon Press, Eugene,2nd edition. 300P
Westerfield, M. and Liu, D.W. (1993) Cellular interactions regulating the formation of terminal arbors by primary motoneurons in the zebrafish. In Cell-Cell Signaling in Vertebrate Development, E. Robertson, F.R. Maxfield, and H.J. Vogel, eds., Academic Press. 113-122
Westerfield, M., Akimenko, M.A., Ekker, M., and Püschel, A. (1993) Eyes, ears and homeobox genes in zebrafish embryos. In Molecular Basis of Morphogenesis, M. Bernfield, ed., New York, NY: John Wiley & Sons, Wiley-Liss Division. 67-75
Westerfield, M., Stuart, G., and Wegner, J. (1993) Expression of foreign genes in zebrafish embryos. In Devel. Ind. Microbiol., Vol II, William C. Brown, ed., New York. 658-665
Ekker, M., Akimenko, M.A., BreMiller, R., and Westerfield, M. (1992) Regional expression of three homeobox transcripts in the inner ear of zebrafish embryos. Neuron. 9:27-35
Ekker, M., Fritz, A., and Westerfield, M. (1992) Identification of two families of satellite-like repetitive DNA sequences from the zebrafish (Brachydanio rerio). Genomics. 13:1169-1173
Ekker, M., Wegner, J., Akimenko, M.A., and Westerfield, M. (1992) Coordinate embryonic expression of three zebrafish engrailed genes. Development. 116:1001-1010
Goff, D.J., Galvin, K., Katz, H., Westerfield, M., Lander, E.S., and Tabin, C.J. (1992) Identification of polymorphic simple sequence repeats in the genome of the zebrafish. Genomics. 14:200-202
Liu, D.W. and Westerfield, M. (1992) Clustering of muscle acetylcholine receptors requires motoneurons in live embryos but not in cell culture. J. Neurosci.. 12:1859-1866
Püschel, A.W., Gruss, P., and Westerfield, M. (1992) Sequence and expression pattern of pax-6 are highly conserved between zebrafish and mice. Development. 114:643-651
Püschel, A.W., Westerfield, M., and Dressler, G.R. (1992) Comparative analysis of Pax-2 protein distributions during neurulation in mice and zebrafish. Mech. Dev.. 38:197-208
Westerfield, M. (1992) Motor axon pathfinding. Curr. Opin. Neurobiol.. 2:28-30
Westerfield, M. (1992) Zebrafish Hox and Pax genes. Neurosci. Facts. 3:3
Westerfield, M., Wegner, J., Jegalian, B.G., De Robertis, E.M., and Püschel, A.W. (1992) Specific activation of mammalian Hox promoters in mosaic transgenic zebrafish. Genes Dev.. 6:591-598
Ekker, M., Akimenko, M.A., BreMiller, R., and Westerfield, M. (1991) Characterization of four homeobox genes expressed in zebrafish neural crest. Soc. Neurosci. Abstr.. 17:924
Hatta, K., BreMiller, R.A., Westerfield, M., and Kimmel, C.B. (1991) Diversity of expression of engrailed-like antigens in zebrafish. Development. 112:821-832
Westerfield, M., Wegner, J., Akimenko, M., Ekker, M., Eisen, J., and Halpern, M. (1991) A role for engrailed gene in zebrafish muscle patterning. Soc. Neurosci. Abstr.. 17:761
Akimenko, M.A., Ekker, M., and Westerfield, M. (1990) Characterization of three zebrafish genes related to Hox-7. In Developmental Patterning of the Vertebrate Limb, J.R. Hinchliffe, J. Hurle and D. Summerbell, eds., New York: Plenum Press. 61-63
Felsenfeld, A.L., Walker, C., Westerfield, M., Kimmel, C., and Streisinger, G. (1990) Mutations affecting skeletal muscle myofibril structure in the zebrafish. Development. 108:443-459
Kimmel, C.B. and Westerfield, M. (1990) Primary neurons of the zebrafish. In Signal and Sense, G.M. Edelman, W.E. Gall, and M.W. Cowan, eds., New York: Wiley-Liss. 561-588
Liu, D.W.C. and Westerfield, M. (1990) The formation of terminal fields in the absence of competitive interactions among primary motoneurons in the zebrafish. J. Neurosci.. 10:3947-3959
Metcalfe, W.K. and Westerfield, M. (1990) Primary motoneurons of the zebrafish. In Systems Approaches to Developmental Neurobiology, P.A. Raymond, S.S. Easter and G.M. Innocenti, eds., NATO ASI Series A,New York: Plenum Press. 192:41-47
Stuart, G.W., Vielkind, J.R., McMurray, J.V., and Westerfield, M. (1990) Stable lines of transgenic zebrafish exhibit reproducible patterns of transgene expression. Development. 109:577-584
Westerfield, M. (1990) Does the mesoderm induce Hox gene expression in the zebrafish nervous system?. Soc. Neurosci. Abstr.. 16:302
Westerfield, M., Liu, D.W., Kimmel, C.B., and Walker, C. (1990) Pathfinding and synapse formation in a zebrafish mutant lacking functional acetylcholine receptors. Neuron. 4:867-874
Debu B., Frost, D., Westerfield M., Eisen J.S. (1989) Patterning of primary motoneuron axonal outgrowth by extracellular matrix molecules in zebrafish embryos. Soc. Dev. Biol. Mtg. Abstr.
Hanneman, E. and Westerfield, M. (1989) Early expression of acetylcholinesterase activity in functionally distinct neurons of the zebrafish. J. Comp. Neurol.. 284:350-361
Liu, D.W. and Westerfield, M. (1989) Primary motoneurons instruct muscle acetylcholine receptor placement but receptors don't instruct motoneuronal synapse placement in live zebrafish. Soc. Neurosci. Abstr.. 15:1262
Stuart, G.W., McMurray, J.V., and Westerfield, M. (1989) Germ-line transformation of the zebrafish. In Gene Transfer and Gene Therapy, A.L. Beaudet, R. Mulligan, and I. M. Verma, eds., New York, NY, USA: Alan R. Liss, Inc.. 19-28
Westerfield, M. (1989) Establishment of cell-specific differences among primary motoneurons in the zebrafish. In The Assembly of the Nervous System. Landmesser, L.T., ed., New York, NY, USA: Alan R. Liss, Inc.. 189-198
Westerfield, M. (1989) The Zebrafish Book; A Guide for the Laboratory Use of Zebrafish (Brachydanio rerio). University of Oregon Press, Eugene.
Bass, M.B. and Westerfield, M. (1988) Purification of neuron-specific antigens from zebrafish. Soc. Neurosci. Abstr.. 14:1267
Frost, D., Debu B., Eisen J.S., and Westerfield M. (1988) Axonal outgrowth in embryonic zebrafish is perturbed by ectopic localization of fibronectin in vivo. Soc. Dev. Biol. Mtg. Abstr.
Grunwald, D.J., Kimmel, C.B., Westerfield, M., Walker, C., and Streisinger, G. (1988) A neural degeneration mutation that spares primary neurons in the zebrafish. Dev. Biol.. 126:115-128
Hanneman, E., Trevarrow, B., Metcalfe, W.K., Kimmel, C.B., and Westerfield, M. (1988) Segmental pattern of development of the hindbrain and spinal cord of the zebrafish embryo. Development. 103:49-58
Liu, D.W. and Westerfield, M. (1988) Function of identified motoneurones and co-ordination of primary and secondary motor systems during zebra fish swimming. J. Physiol. Lond.. 403:73-89
Stuart, G.W., McMurray, J.V., and Westerfield, M. (1988) Germ-line transformation of the zebrafish Brachydanio-rerio. J. Cell. Biochem.. (Suppl.) 12:195
Stuart, G.W., McMurray, J.V., and Westerfield, M. (1988) Replication, integration and stable germ-line transmission of foreign sequences injected into early zebrafish embryos. Development. 103:403-412
Westerfield, M. and Eisen, J.S. (1988) Neuromuscular specificity: pathfinding by identified motor growth cones in a vertebrate embryo. Trends Neurosci.. 11:18-22
Liu, D.W. and Westerfield, M. (1987) The formation of terminal fields by identified motoneurons in the zebrafish. Anim. Behav.. 35:1875-1882
Westerfield, M. (1987) Substrate interactions affecting motor growth cone guidance during development and regeneration. J. Exp. Biol.. 132:161-176
Westerfield, M. and Eisen, J.S. (1987) Common mechanisms of growth cone guidance during axonal pathfinding. In From Message to Mind: New Directions in the Developmental Neurobiology, Sinauer Assoc.. 110-120
Westerfield, M., Kimmel, C.B., and Walker, C. (1987) Normal pathfinding by pioneer motor growth cones in mutant zebrafish lacking functional acetylcholine receptors. Soc. Neurosci. Abstr.. 13:5
Eisen, J.S., Myers, P.Z., and Westerfield, M. (1986) Pathway selection by growth cones of identified motoneurones in live zebra fish embryos. Nature. 320(6059):269-271
Felsenfeld, A. and Westerfield, M. (1986) Normal pathfinding and synapse formation by motoneurons in a non-motile mutant zebrafish embryo. Soc. Neurosci. Abstr.. 147:12
Frost, D. and Westerfield, M. (1986) Axonal outgrowth of embryonic zebrafish neurons is promoted by laminin and inhibited by fibronectin. Soc. Neurosci. Abstr.. 12:1114
Liu, D. and Westerfield, M. (1986) Coactivation of two motor systems in the zebrafish. Soc. Neurosci. Abstr.. 2:790
Myers, P.Z., Eisen, J.S., and Westerfield, M. (1986) Development and axonal outgrowth of identified motoneurons in the zebrafish. J. Neurosci.. 6:2278-2289
Westerfield, M., Eisen, J.S., Myers, P.Z., McMurray, J.V., and Kimmel, C.B. (1986) Early neurogenesis in the zebrafish. Proc. Int. Union Physiol. Sci.. 16:20
Westerfield, M., McMurray, J.V., and Eisen, J.S. (1986) Identified motoneurons and their innervation of axial muscles in the zebrafish. J. Neurosci.. 6:2267-2277
Eisen, J.S., Myers, P.Z., and Westerfield, M. (1985) Functional interactions between identified growth cones and muscles in embryonic zebrafish. Soc. Neurosci. Abstr.. 11:586
Kimmel, C.B., Grunwald, D.J., Walker, C., Westerfield, M., and Streisinger, G. (1985) Neuronal degeneration mutations that spare primary neurons in the zebrafish. Soc. Neurosci. Abstr.. 11:647
Westerfield, M. and Eisen, J.S. (1985) The growth of motor axons in the spinal cord of Xenopus embryos. Dev. Biol.. 109:96-121
Eisen, J.S., Myers, P.Z., and Westerfield, M. (1984) Segmentally specific growth of motor axons in live zebrafish embryos. Soc. Neurosci. Abstr.. 10:371
Hanneman, E. and Westerfield, M. (1984) Identified neurons produce acetylcholinesterase before they sprout axons in the zebrafish. Soc. Neurosci. Abstr.. 10:1043
Westerfield, M., Myers, P.Z., and Eisen, J.S. (1984) Polyneuronal and intersegmental innervation of body muscles in the zebrafish. Soc. Neurosci. Abstr.. 10:371