Gene

rev1

ID
ZDB-GENE-081105-180
Name
REV1 DNA directed polymerase
Symbol
rev1 Nomenclature History
Previous Names
  • si:dkey-57a22.7
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have DNA-directed DNA polymerase activity and deoxycytidyl transferase activity. Predicted to be involved in error-free translesion synthesis and error-prone translesion synthesis. Predicted to localize to nucleus. Orthologous to human REV1 (REV1 DNA directed polymerase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Chen et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rev1 Human Ortholog
No data available
Associated With rev1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR025527 HUWE1/REV1, ubiquitin-binding motif
Conserved_site IPR047346 DNA repair protein REV1, ubiquitin-binding motif 1/2
Domain IPR001126 UmuC domain
Domain IPR001357 BRCT domain
Domain IPR017961 DNA polymerase, Y-family, little finger domain
Domain IPR031991 DNA repair protein Rev1, C-terminal
Family IPR012112 DNA repair protein Rev1
Homologous_superfamily IPR036420 BRCT domain superfamily
Homologous_superfamily IPR036775 DNA polymerase, Y-family, little finger domain superfamily
Homologous_superfamily IPR038401 Rev1, C-terminal domain superfamily
Homologous_superfamily IPR043128 Reverse transcriptase/Diguanylate cyclase domain
Homologous_superfamily IPR043502 DNA/RNA polymerase superfamily
Domain Details Per Protein
Protein Length BRCT domain BRCT domain superfamily DNA polymerase, Y-family, little finger domain DNA polymerase, Y-family, little finger domain superfamily DNA repair protein Rev1 DNA repair protein Rev1, C-terminal DNA repair protein REV1, ubiquitin-binding motif 1/2 DNA/RNA polymerase superfamily HUWE1/REV1, ubiquitin-binding motif Rev1, C-terminal domain superfamily Reverse transcriptase/Diguanylate cyclase domain UmuC domain
UniProtKB:A0A8M6Z8G9 1201
UniProtKB:A0A8M3AVZ1 1261
UniProtKB:A0A8M2BF27 1262
UniProtKB:B0UY97 1268
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations