Gene

ptprq

ID

ZDB-GENE-050419-183

Name

protein tyrosine phosphatase receptor type Q

Symbol

ptprq Nomenclature History

Previous Names

si:ch211-11f8.3 (1)

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 73 and autosomal recessive nonsyndromic deafness 84A. Orthologous to human PTPRQ (protein tyrosine phosphatase receptor type Q).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from van Eekelen et al., 2010

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptprq Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal dominant nonsyndromic deafness 73	Alliance	Deafness, autosomal dominant 73	617663
autosomal recessive nonsyndromic deafness 84A	Alliance	Deafness, autosomal recessive 84A	613391

Associated With ptprq Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR003961	Fibronectin type III
Family	IPR050713	Receptor-type Tyrosine-protein Phosphatases/Ushers
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR036116	Fibronectin type III superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin-like fold	Protein-tyrosine phosphatase, active site	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Receptor-type Tyrosine-protein Phosphatases/Ushers	Tyrosine-specific protein phosphatase, PTPase domain	Tyrosine-specific protein phosphatases domain
UniProtKB:A0AB32T5C6	InterPro	2382

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ptprq-202 (1) Ensembl	Ensembl		6,906 nt	Select Tool ZFIN BLAST
ncRNA	ptprq-002 (1) Ensembl	Ensembl		523 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations