Gene
actc2
- ID
- ZDB-GENE-040625-35
- Name
- actin, alpha, cardiac muscle 2
- Symbol
- actc2 Nomenclature History
- Previous Names
-
- zgc:86709 (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity. Predicted to be involved in mesenchyme migration and positive regulation of gene expression. Predicted to localize to several cellular components, including cell body; filopodium; and lamellipodium. Human ortholog(s) of this gene implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11. Is expressed in heart tube and post-vent region. Orthologous to human ACTC1 (actin alpha cardiac muscle 1).
- Genome Resources
- Note
-
The nomenclature for this gene was based on evidence from Witjes et al. (2019) and in collaboration with HGNC and MGI.
- Comparative Information
-
- All Expression Data
- 2 figures from Ojehomon et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin/actin-like conserved site | Actin, conserved site | Actin family | ATPase, nucleotide binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6IQL9
|
377 |
Interactions and Pathways
No data available
Plasmids
No data available