Gene
hdac3
- ID
- ZDB-GENE-040426-847
- Name
- histone deacetylase 3
- Symbol
- hdac3 Nomenclature History
- Previous Names
-
- zgc:55927 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable chromatin binding activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; and transcription corepressor activity. Acts upstream of or within several processes, including angiogenesis; liver development; and posterior lateral line development. Predicted to be located in cytoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Is expressed in several structures, including axial blood vessel; blood vessel; digestive system; otic vesicle; and sensory system. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human HDAC3 (histone deacetylase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55927 (1 image)
- MGC:55927 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Histone deacetylase domain | Histone deacetylase domain superfamily | Ureohydrolase domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q803C3 | InterPro | 428 |
Interactions and Pathways
No data available
Plasmids
No data available