ZFIN is now using GRCz12tu for Genomic Data
Gene
cdk2
- ID
- ZDB-GENE-040426-2741
- Name
- cyclin dependent kinase 2
- Symbol
- cdk2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in G2/M transition of mitotic cell cycle and signal transduction. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system and head. Human ortholog(s) of this gene implicated in ovarian disease; prostate cancer; and renal cell carcinoma. Orthologous to human CDK2 (cyclin dependent kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 33 figures from 24 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56598 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Yang et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cyclin-dependent kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q7ZWB1 | InterPro | 298 | |||||
| UniProtKB:A0AC58GPZ5 | InterPro | 208 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers