Gene
llgl2
- ID
- ZDB-GENE-030131-9877
- Name
- LLGL scribble cell polarity complex component 2
- Symbol
- llgl2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity; Rab GTPase binding activity; and myosin II binding activity. Involved in several processes, including Kupffer's vesicle development; hemidesmosome assembly; and motile cilium assembly. Predicted to localize to cortical actin cytoskeleton and plasma membrane. Is expressed in several structures, including EVL; Kupffer's vesicle; digestive system; mesoderm; and sensory system. Orthologous to human LLGL2 (LLGL scribble cell polarity complex component 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb521 (18 images)
- IMAGE:7154746 (19 images)
Wild Type Expression Summary
- All Phenotype Data
- 18 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013577 | Lethal giant larvae homologue 2 |
| Family | IPR000664 | Lethal(2) giant larvae protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | Lethal(2) giant larvae protein | Lethal giant larvae homologue 2 | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7SZE3
|
1020 | |||||
|
UniProtKB:B7ZVM2
|
1020 | |||||
|
UniProtKB:A0A8M9QMN2
|
1004 |
Interactions and Pathways
No data available
Plasmids
No data available