Gene

llgl2

ID
ZDB-GENE-030131-9877
Name
LLGL scribble cell polarity complex component 2
Symbol
llgl2 Nomenclature History
Previous Names
  • lgl2 (1)
  • cb521 (1)
  • pen
  • penner
  • sb:cb521
  • wu:fc06g08
  • wu:fl37c09
  • zgc:55895
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity; Rab GTPase binding activity; and myosin II binding activity. Involved in several processes, including Kupffer's vesicle development; hemidesmosome assembly; and motile cilium assembly. Predicted to localize to cortical actin cytoskeleton and plasma membrane. Is expressed in several structures, including EVL; Kupffer's vesicle; digestive system; mesoderm; and sensory system. Orthologous to human LLGL2 (LLGL scribble cell polarity complex component 2).
Genome Resources
Note
None
Expression
All Expression Data
22 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
18 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With llgl2 Human Ortholog
No data available
Associated With llgl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR013577 Lethal giant larvae homologue 2
Domain IPR017986 WD40-repeat-containing domain
Family IPR000664 Lethal(2) giant larvae protein
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Lethal(2) giant larvae protein Lethal giant larvae homologue 2 WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A2R8Q3V3 1004
UniProtKB:G1K2W2 154
UniProtKB:Q7SZE3 1020
UniProtKB:B7ZVM2 1020
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-llgl2 polyclonal
  • IHC
  • WB
8
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations