ZFIN ID: ZDB-GENE-030131-9877
Gene Name: LLGL scribble cell polarity complex component 2
Gene Symbol: llgl2
Sequence Ontology ID : SO:0000704

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Previous Names: lgl2 (1), cb521 (1), pen, penner, sb:cb521, wu:fc06g08, wu:fl37c09, zgc:55895

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have GTPase activator activity and Rab GTPase binding activity; involved in several processes, including Kupffer's vesicle development, animal organ development, and cytoskeleton  ...
GENE EXPRESSION
All Expression Data: 20 figures from 7 publications
Directly Submitted Expression Data: 6 figures (18 images) from Thisse et al., 2001 [cb521]
  6 figures (19 images) from Thisse et al., 2004 [IMAGE:7154746]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012203Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018226Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31887 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38900 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • to6 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 13 figures from 6 publications
    Observed in:
    DISEASE ASSOCIATED WITH llgl2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH llgl2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell projection assembly (more)
    Cellular Component cytoplasm (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 24)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000664 (1)
  • InterPro:IPR001680 (1)
  • InterPro:IPR013577 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR017986 (1)
  • InterPro:IPR019775 (1)
  • InterPro:IPR036322 (1)
  • PROSITE:PS00678 (1)
  • PROSITE:PS50082 (1)
  • PROSITE:PS50294 (1)
  • Pfam:PF08366 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA llgl2-001 (1) 4300
    ncRNA llgl2-002 (1) 503
    llgl2-003 (1) 610
    mRNA llgl2-004 (1) 950
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM llgl2 No data available
    MARKER RELATIONSHIPS
    llgl2Contained in: [BAC] CH73-77C22 (1) (order this), DKEYP-67E6 (1)
    [Fosmid] CH1073-342O4 (1) (order this)
    llgl2Encodes: [EST] cb521 (1) (order this), fc06g08 (1), fl37c09 (1), IMAGE:7154746 (1) (order this)
    [cDNA] MGC:55895 (1) (order this), MGC:198362 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212582 (1) 4287bp
    Genomic GenBank:CR405682 (1) 192457bp
    Select Tool
    Polypeptide UniProtKB:B7ZVM2 (1) 1020aa
    Sequence Clusters UniGene:76731 (1)
    Sequence Information (all 29)
    OTHER llgl2 GENE PAGES
  • Alliance (1)
  • Gene:795670 (1)
  • VEGA:OTTDARG00000020630 (1)
  • Ensembl(GRCz11):ENSDARG00000023920 (2)
  • ORTHOLOGY for llgl2 (Chr: 12)
    CITATIONS (47)