Gene
plcg2
- ID
- ZDB-GENE-030131-9532
- Name
- phospholipase C, gamma 2
- Symbol
- plcg2 Nomenclature History
- Previous Names
-
- fj85b03
- sb:eu1064
- si:ch211-260p9.2
- wu:fj85b03
- zgc:152893
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have phosphatidylinositol phospholipase C activity. Predicted to be involved in several processes, including inositol trisphosphate biosynthetic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Human ortholog(s) of this gene implicated in familial cold autoinflammatory syndrome 3. Orthologous to human PLCG2 (phospholipase C gamma 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1064 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
familial cold autoinflammatory syndrome 3 | Alliance | Familial cold autoinflammatory syndrome 3 | 614468 |
Autoinflammation, antibody deficiency, and immune dysregulation syndrome | 614878 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein | Length | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q1LWV8
|
1240 |
Interactions and Pathways
No data available
Plasmids
No data available