OBO ID: DOID:9119

OBO ID: DOID:9119

Citations

(35 total)

Belt, A.J., Grant, S., Tombes, R.M., Rothschild, S.C. (2024) Myeloid Targeted Human MLL-ENL and MLL-AF9 Induces cdk9 and bcl2 Expression in Zebrafish Embryos. PLoS Genetics. 20:e1011308e1011308

Sun, R., Sun, L., Xie, X., Li, X., Wu, P., Wang, L., Zhu, P. (2022) Single-cell analysis of transcription factor regulatory networks reveals molecular basis for subtype-specific dysregulation in acute myeloid leukemia. Blood science (Baltimore, Md.). 4:65-75

Fang, X., Xu, S., Zhang, Y., Xu, J., Huang, Z., Liu, W., Wang, S., Yen, K., Zhang, W. (2021) Asxl1 C-terminal mutation perturbs neutrophil differentiation in zebrafish. Leukemia. 35(8):2299-2310

Selvaraju, K., Lotfi, K., Gubat, J., Miquel, M., Nilsson, A., Hill, J., Jensen, L.D., Linder, S., D'Arcy, P. (2021) Sensitivity of Acute Myelocytic Leukemia Cells to the Dienone Compound VLX1570 Is Associated with Inhibition of the Ubiquitin-Proteasome System. Biomolecules. 11(9):

Weinreb, J.T., Gupta, V., Sharvit, E., Weil, R., Bowman, T.V. (2021) Ddx41 inhibition of DNA damage signaling permits erythroid progenitor expansion in zebrafish. Haematologica. 107(3):644-654

Yu, X., Munoz-Sagredo, L., Streule, K., Muschong, P., Bayer, E., Walter, R.J., Gutjahr, J.C., Greil, R., Concha, M.L., Müller-Tidow, C., Hartmann, T.N., Orian-Rousseau, V. (2021) CD44 loss of function sensitizes AML cells to the BCL-2 inhibitor venetoclax by decreasing CXCL12-driven survival cues. Blood. 138(12):1067-1080

He, B.L., Yang, N., Man, C.H., Ng, N.K., Cher, C.Y., Leung, H.C., Kan, L.L., Cheng, B.Y., Lam, S.S., Wang, M.L., Zhang, C.X., Kwok, H., Cheng, G., Sharma, R., Ma, A.C., So, C.E., Kwong, Y.L., Leung, A.Y. (2020) Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia. EMBO Molecular Medicine. 12(4):e10895

Kang, J.W., Kim, Y., Lee, Y., Myung, K., Kim, Y.H., Oh, C.K. (2020) AML poor prognosis factor, TPD52, is associated with the maintenance of haematopoietic stem cells through regulation of cell proliferation. Journal of cellular biochemistry. 122(3-4):403-412

Mazzola, M., Pezzotta, A., Fazio, G., Rigamonti, A., Bresciani, E., Gaudenzi, G., Pelleri, M.C., Saitta, C., Ferrari, L., Parma, M., Fumagalli, M., Biondi, A., Cazzaniga, G., Marozzi, A., Pistocchi, A. (2020) Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects. Journal of Cellular and Molecular Medicine. 24(11):6272-6282

Spreafico, M., Gruszka, A.M., Valli, D., Mazzola, M., Deflorian, G., Quintè, A., Totaro, M.G., Battaglia, C., Alcalay, M., Marozzi, A., Pistocchi, A. (2020) HDAC8: A Promising Therapeutic Target for Acute Myeloid Leukemia. Frontiers in cell and developmental biology. 8:844

Gjini, E., Jing, C.B., Nguyen, A.T., Reyon, D., Gans, E., Kesarsing, M., Peterson, J., Pozdnyakova, O., Rodig, S.J., Mansour, M.R., Joung, K., Look, A.T. (2019) Disruption of asxl1 results in myeloproliferative neoplasms in zebrafish. Disease models & mechanisms. 12(5):

Khan, N., Bammidi, S., Jayandharan, G.R. (2019) A CD33 antigen targeted AAV6 vector expressing an inducible caspase-9 suicide gene is therapeutic in a xenotransplantation model of acute myeloid leukemia. Bioconjugate Chemistry. 30(9):2404-2416

Mazzola, M., Deflorian, G., Pezzotta, A., Ferrari, L., Fazio, G., Bresciani, E., Saitta, C., Ferrari, L., Fumagalli, M., Parma, M., Marasca, F., Bodega, B., Riva, P., Cotelli, F., Biondi, A., Marozzi, A., Cazzaniga, G., Pistocchi, A. (2019) NIPBL: a new player in myeloid cells differentiation. Haematologica. 104(7):1332-1341

Vicente, C., Arriazu, E., Martínez-Balsalobre, E., Peris, I., Marcotegui, N., García-Ramírez, P., Pippa, R., Rabal, O., Oyarzábal, J., Guruceaga, E., Prósper, F., Mateos, M.C., Cayuela, M.L., Odero, M.D. (2019) A novel FTY720 analogue targets SET-PP2A interaction and inhibits growth of acute myeloid leukemia cells without inducing cardiac toxicity. Cancer letters. 468:1-13

Khan, N., Mahajan, N.K., Sinha, P., Jayandharan, G.R. (2018) An efficient method to generate xenograft tumor models of acute myeloid leukemia and hepatocellular carcinoma in adult zebrafish. Blood cells, molecules & diseases. 75:48-55

Piragyte, I., Clapes, T., Polyzou, A., Klein Geltink, R.I., Lefkopoulos, S., Yin, N., Cauchy, P., Curtis, J.D., Klaeylé, L., Langa, X., Beckmann, C.C.A., Wlodarski, M.W., Müller, P., Van Essen, D., Rambold, A., Kapp, F.G., Mione, M., Buescher, J.M., Pearce, E.L., Polyzos, A., Trompouki, E. (2018) A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nature communications. 9:3090

Smith, K.M., Fagan, P.C., Pomari, E., Germano, G., Frasson, C., Walsh, C., Silverman, I., Bonvini, P., Li, G. (2018) Antitumor Activity of Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor, in ETV6-NTRK3-Positive Acute Myeloid Leukemia. Molecular cancer therapeutics. 17:455-463

Tan, J., Zhao, L., Wang, G., Li, T., Li, D., Xu, Q., Chen, X., Shang, Z., Wang, J., Zhou, J. (2018) Human MLL-AF9 Overexpression Induces Aberrant Hematopoietic Expansion in Zebrafish. BioMed Research International. 2018:6705842

Hou, H.A., Lu, J.W., Lin, T.Y., Tsai, C.H., Chou, W.C., Lin, C.C., Kuo, Y.Y., Liu, C.Y., Tseng, M.H., Chiang, Y.C., Peng, Y.L., Tang, J.L., Gong, Z., Lin, L.I., Tien, H.F. (2017) Clinico-biological significance of suppressor of cytokine signaling 1 expression in acute myeloid leukemia. Blood cancer journal. 7:e588

Liu, W., Wu, M., Huang, Z., Lian, J., Chen, J., Wang, T., Leung, A.Y., Liao, Y., Zhang, Z., Liu, Q., Yen, K., Lin, S., Zon, L.I., Wen, Z., Zhang, Y., Zhang, W. (2017) c-myb hyperactivity leads to myeloid and lymphoid malignancies in zebrafish. Leukemia. 31(1):222-233

Lu, J.W., Hsieh, M.S., Hou, H.A., Chen, C.Y., Tien, H.F., Lin, L.I. (2017) Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish. Blood cancer journal. 7:e593

Oo, Z.M., Illendula, A., Grembecka, J., Schmidt, C., Zhou, Y., Esain, V., Kwan, W., Frost, I., North, T.E., Rajewski, R.A., Speck, N.A., Bushweller, J.H. (2017) A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells. Leukemia & lymphoma. 59(9):2188-2200

Potts, K.S., Bowman, T.V. (2017) Modeling Myeloid Malignancies Using Zebrafish. Frontiers in oncology. 7:297

Zhou, B., Li, H., Xing, C., Ye, H., Feng, J., Wu, J., Lu, Z., Fang, J., Gao, S. (2017) Honokiol induces proteasomal degradation of AML1-ETO oncoprotein via increasing ubiquitin conjugase UbcH8 expression in leukemia. Biochemical pharmacology. 128:12-25

Barbieri, E., Deflorian, G., Pezzimenti, F., Valli, D., Saia, M., Meani, N., Gruszka, A.M., Alcalay, M. (2016) Nucleophosmin leukemogenic mutant activates Wnt signaling during zebrafish development. Oncotarget. 7(34):55302-55312

Lazzaroni, F., Del Giacco, L., Biasci, D., Turrini, M., Prosperi, L., Brusamolino, R., Cairoli, R., Beghini, A. (2016) Intronless WNT10B-short variant underlies new recurrent allele-specific rearrangement in acute myeloid leukaemia. Scientific Reports. 6:37201

Lu, J.W., Hou, H.A., Hsieh, M.S., Tien, H.F., Lin, L.I. (2016) Overexpression of FLT3-ITD driven by spi-1 results in expanded myelopoiesis with leukemic phenotype in zebrafish. Leukemia. 30(10):2098-2101

Tregnago, C., Manara, E., Zampini, M., Bisio, V., Borga, C., Bresolin, S., Aveic, S., Germano, G., Basso, G., Pigazzi, M. (2016) CREB engages C/EBPδ to initiate leukemogenesis. Leukemia. 30(9):1887-96

Deveau, A.P., Forrester, A.M., Coombs, A.J., Wagner, G.S., Grabher, C., Chute, I.C., Léger, D., Mingay, M., Alexe, G., Rajan, V., Liwski, R., Hirst, M., Steigmaier, K., Lewis, S.M., Look, A.T., Berman, J.N. (2015) Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98-HOXA9-induced myeloid disease. Leukemia. 29(10):2086-97

Ma, S., Yang, L.L., Niu, T., Cheng, C., Zhong, L., Zheng, M.W., Xiong, Y., Li, L.L., Xiang, R., Chen, L.J., Zhou, Q., Wei, Y.Q., Yang, S.Y. (2015) SKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML. Scientific Reports. 5:15646

Neumann, T., Benajiba, L., Göring, S., Stegmaier, K., Schmidt, B. (2015) Evaluation of Improved Glycogen Synthase Kinase-3α Inhibitors in Models of Acute Myeloid Leukemia. Journal of medicinal chemistry. 58(22):8907-19

Shen, L., Zhu, J., Chen, F., Lin, W., Cai, J., Zhong, J., Zhong, H. (2015) RUNX1-Evi-1 fusion gene inhibited differentiation and apoptosis in myelopoiesis: an in vivo study. BMC cancer. 15:970

He, B.L., Shi, X., Man, C.H., Ma, A.C., Ekker, S.C., Chow, H.C., So, C.W., Choi, W.W., Zhang, W., Zhang, Y., and Leung, A.Y. (2014) Functions of FMS-like tyrosine kinase 3 (flt3) in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia. Blood. 123(16):2518-29

Wang, Q.F., Li, Y.J., Dong, J.F., Li, B., Kaberlein, J.J., Zhang, L., Arimura, F.E., Luo, R.T., Ni, J., He, F., Wu, J., Mattison, R., Zhou, J., Wang, C.Z., Prabhakar, S., Nobrega, M.A., and Thirman, M.J. (2014) Regulation of MEIS1 by distal enhancer elements in acute leukemia. Leukemia. 28(1):138-46

Warkentin, A.A., Lopez, M.S., Lasater, E.A., Lin, K., He, B., Leung, A.Y., Smith, C.C., Shah, N.P., Shokat, K.M. (2014) Overcoming myelosuppression due to synthetic lethal toxicity for FLT3-targeted acute myeloid leukemia therapy. eLIFE. 3