|
ZFIN ID: ZDB-GENE-990706-8
|
| Gene Name: |
GLI-Kruppel family member GLI2a |
| Gene Symbol: |
gli2a |
|
Previous Names:
|
gli2,
etID12892.9 (1),
fc85b05,
wu:fc85b05 (1),
yot,
you too,
you-too
|
|
Nomenclature
History
|
GENE EXPRESSION
| All Expression Data: |
24
figures
from
15 publications
|
| Directly Submitted Expression Data: |
6
figures
(22
images)
from Thisse et al., 2005
[eu801]
|
| Wild-type Stages, Structures: |
Gastrula:50%-epiboly (5.25h-5.66h)
to
Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
|
| |
adenohypophyseal placode,
anterior neural plate,
central nervous system,
choroidal fissure
(all 29)
adenohypophyseal placode,
anterior neural plate,
central nervous system,
choroidal fissure,
diencephalon,
forebrain,
gut mesenchyme,
hindbrain,
lateral mesoderm,
mesoderm,
midbrain,
midbrain hindbrain boundary,
midbrain neural keel,
neural plate,
optic tectum,
optic vesicle,
pars intermedia,
pectoral fin,
pharyngeal arch,
retina,
rhombomere 4,
rhombomere 5,
rhombomere 6,
segmental plate,
somite,
tail bud,
telencephalon,
unspecified,
whole organism
|
| Curated Microarray Expression: |
GEO (1)
|
MUTANTS AND TARGETED KNOCKDOWNS
| Mutant lines: |
13 genotypes
|
| Alleles: |
gli2a_unspecified,
la016571Tg,
s406,
sa10919,
sa12847
(all 9)
gli2a_unspecified,
la016571Tg,
s406,
sa10919,
sa12847,
sa15237,
sa15798,
ty119,
ty17a
|
| Knockdown reagents: |
MO1-gli2a
(1),
MO2-gli2a
(1)
|
PHENOTYPE
| Data: |
41 figures
from
24 publications
|
| Observed in: |
adaxial cell,
adenohypophysis,
adenohypophysis morphogenesis,
adrenocorticotropic hormone secreting cell
(all 66)
adaxial cell,
adenohypophysis,
adenohypophysis morphogenesis,
adrenocorticotropic hormone secreting cell,
anterior commissure,
axon guidance,
blood circulation,
blood vessel morphogenesis,
brain,
CaP motoneuron axon,
central nervous system projection neuron axonogenesis,
ceratobranchial 5 bone,
ceratobranchial 5 tooth,
chondrocranium,
corticotropin hormone secreting cell differentiation,
cranial neural crest cell,
diencephalon,
dorsal aorta,
ethmoid cartilage,
eye,
facial nerve motor nucleus,
fast muscle cell,
floor plate,
floor plate formation,
forebrain,
forebrain regionalization,
hindbrain,
horizontal myoseptum,
larval locomotory behavior,
lateral floor plate,
lens,
MiP motor neuron axon,
muscle cell differentiation,
muscle pioneer,
muscle precursor cell,
musculoskeletal movement,
myoseptum,
myotome,
nervous system,
neural tube,
optic chiasm,
optic nerve formation,
pars anterior,
pericardium,
pharyngeal arch 3-7,
post-vent region,
posterior cardinal vein,
postoptic commissure,
proctodeum,
response to external stimulus,
retinal ganglion cell axon,
retinal ganglion cell axon guidance,
Rohon-Beard neuron,
sensory neuron,
skeletal muscle tissue development,
slow muscle cell,
smoothened signaling pathway,
somatotropin secreting cell,
somite,
somitogenesis,
striated muscle cell development,
third ventricle,
trabecula cranii,
trigeminal motor nucleus,
vagal lobe,
whole organism
|
| Phenotype of Human Orthologue |
OMIM Phenotype ID |
|
Holoprosencephaly-9
|
610829
|
TRANSCRIPTS
| Type |
Name |
Length (bp) |
Analysis
|
|
|
mRNA
|
gli2a-001
(1)
|
6039
|
|
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GENE PRODUCT DESCRIPTION
No description available
CONSTRUCTS WITH SEQUENCES FROM gli2a
SEGMENT (CLONE AND PROBE) RELATIONSHIPS
Request: