Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-43
Gene Name: cytochrome P450, family 19, subfamily A, polypeptide 1a
Gene Symbol: cyp19a1a
Previous Names: ar1, cyp19, cyp19a (1), CYP19a1 (1), cypXIX, aromatase, etID309862.18 (1), P450aromA, zgc:136541 (1)
Location: Chr: 18   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 37 figures from 21 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, eye, female organism gonad, gonad (all 17) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Aromatase deficiency 613546
Aromatase excess syndrome 139300
GENE ONTOLOGY
Ontology GO Term
Biological Process response to estradiol (more)
Cellular Component membrane (more)
Molecular Function heme binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002401 (1)
  • InterPro:IPR017972 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • EC:1.14.14.14 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp19a1a-001 (1) 1862
    ncRNA cyp19a1a-002 (1) 1673
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp19a1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp19a1a Contained in: [BAC] CH211-165A16 (1) (order this)
    cyp19a1a Encodes: [cDNA] MGC:136541 (1) (order this), MGC:194465 (1), MGC:194471 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131154 (1) 1786 bp
    Genomic GenBank:BX908722 (1) 166917 bp
    Select Tool
    Polypeptide UniProtKB:Q1LV36 (1) 517 aa
    Sequence Clusters UniGene:75765 (1)
    Sequence Information (all 32)
    OTHER cyp19a1a GENE PAGES
  • Gene:30390 (1)
  • VEGA:OTTDARG00000013418 (1)
  • Ensembl(Zv9):ENSDARG00000041348 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish cyp19a1a 18  
    Human CYP19A1 15 (15q21.1)
  • OMIM:107910
  • Gene:1588
  • Mouse Cyp19a1 9 ( 29.49 cM)
  • MGI:88587
  • Gene:13075
  • Orthology Details
    CITATIONS (87)