ZFIN ID: ZDB-GENE-990415-43
Gene Name: cytochrome P450, family 19, subfamily A, polypeptide 1a
Gene Symbol: cyp19a1a
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: ar1, cyp19, CYP19a1 (1), cyp19a (1), cypXIX, aromatase, etID309862.18 (1), P450aromA (1), zgc:136541 (1)

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 52 figures from 30 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, eye, female organism (all 20) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb158 Small Deletion Unknown Unknown CRISPR
ihb159 Small Deletion Unknown Unknown CRISPR
uc38 Small Deletion Unknown Frameshift, Premature Stop TALEN
uc43 Small Deletion Unknown Frameshift, Premature Stop TALEN
umo5 Small Deletion Unknown Unknown TALEN
umo6 Small Deletion Unknown Unknown CRISPR
umo7 Indel Unknown Unknown CRISPR
Targeting reagents: CRISPR1-cyp19a1a (1), CRISPR2-cyp19a1a (1), MO1-cyp19a1a (1), TALEN1-cyp19a1a (1), TALEN2-cyp19a1a (1)
PHENOTYPE
Data: 3 figures from 3 publications
Observed in: female organism, female sex determination, germ line cell apoptotic process, male gamete generation (all 8) expand
DISEASE ASSOCIATED WITH cyp19a1a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
aromatase excess syndrome Aromatase excess syndrome 139300
Aromatase deficiency 613546
GENE ONTOLOGY
Ontology GO Term
Biological Process response to estradiol (more)
Cellular Component integral component of membrane (more)
Molecular Function heme binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128
  • InterPro:IPR002401
  • InterPro:IPR017972
  • PROSITE:PS00086
  • Pfam:PF00067
  • EC:1.14.14.14
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp19a1a-001 (1) 1862
    ncRNA cyp19a1a-002 (1) 1673
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cyp19a1a
    tgbac(cyp19a1a:egfp)
    MARKER RELATIONSHIPS
    cyp19a1aContained in: [BAC] CH211-165A16 (1) (order this)
    cyp19a1aEncodes: [cDNA] MGC:136541 (1) (order this), MGC:194465 (1), MGC:194471 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131154 (1) 1863bp
    Genomic GenBank:BX908722 (1) 166917bp
    Select Tool
    Polypeptide UniProtKB:Q1LV36 517aa
    Sequence Clusters UniGene:75765 (1)
    Sequence Information (all 30)
    OTHER cyp19a1a GENE PAGES
  • Gene:30390 (1)
  • VEGA:OTTDARG00000013418 (1)
  • Ensembl(GRCz10):ENSDARG00000041348 (1)
  • ORTHOLOGY for cyp19a1a (Chr: 18)
    CITATIONS (168)