ZFIN ID: ZDB-GENE-990415-43
Gene Name: cytochrome P450, family 19, subfamily A, polypeptide 1a
Gene Symbol: cyp19a1a
Previous Names: ar1, cyp19, CYP19a1 (1), cyp19a (1), cypXIX, aromatase, etID309862.18 (1), P450aromA, zgc:136541 (1)
Location: Chr: 18 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 38 figures from 22 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, eye, female organism gonad (all 18) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cyp19a1a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Aromatase excess syndrome 139300
Aromatase deficiency 613546
GENE ONTOLOGY
Ontology GO Term
Biological Process response to estradiol (more)
Cellular Component integral component of membrane (more)
Molecular Function heme binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002401 (1)
  • InterPro:IPR017972 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • EC:1.14.14.14 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp19a1a-001 (1) 1862
    ncRNA cyp19a1a-002 (1) 1673
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cyp19a1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp19a1aContained in: [BAC] CH211-165A16 (1) (order this)
    cyp19a1aEncodes: [cDNA] MGC:136541 (1) (order this), MGC:194465 (1), MGC:194471 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131154 (1) 1786bp
    Genomic GenBank:BX908722 (1) 166917bp
    Select Tool
    Polypeptide UniProtKB:Q1LV36 (1) 517aa
    Sequence Clusters UniGene:75765 (1)
    Sequence Information (all 32)
    OTHER cyp19a1a GENE PAGES
  • Gene:30390 (1)
  • VEGA:OTTDARG00000013418 (1)
  • Ensembl(GRCz10):ENSDARG00000041348 (1)
  • ORTHOLOGY for cyp19a1a (Chr: 18)
    Species Symbol Chromosome Accession # Evidence
    Human CYP19A1 15
  • Gene:1588
  • OMIM:107910
  • HGNC:2594
  • Amino acid sequence comparison (5)
    Conserved genome location (synteny) (2)
    Mouse Cyp19a1 9
  • MGI:88587
  • Gene:13075
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (115)