Gene
nr2f2
- ID
- ZDB-GENE-990415-252
- Name
- nuclear receptor subfamily 2, group F, member 2
- Symbol
- nr2f2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase II regulatory region sequence-specific DNA binding activity; nuclear receptor activity; and retinoic acid binding activity. Involved in circulatory system development and cranial skeletal system development. Predicted to localize to nucleus. Is expressed in several structures, including brain; head; hindbrain neural keel; midbrain neural tube; and neural crest cell. Orthologous to human NR2F2 (nuclear receptor subfamily 2 group F member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 30 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- s80986 (32 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| 46,XX sex reversal 5 | Alliance | 46XX sex reversal 5 | 618901 |
| Congenital heart defects, multiple types, 4 | 615779 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nuclear hormone receptor | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|
|
UniProtKB:Q91430
|
422 |
Interactions and Pathways
Plasmids
No data available