ZFIN ID: ZDB-GENE-980526-135
Gene Name: Indian hedgehog homolog b
Gene Symbol: ihhb
Previous Names: ehh (1), hh[b] (1), hhb, echidna hedgehog, zgc:113262
Location: Chr: 6 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 25 figures from 25 publications
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Larval:Day 6 (144.0h-168.0h)
  axis, ceratohyal bone, ceratohyal cartilage chondrocyte, diencephalon ventral region (all 18) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa20623 Point Mutation ENU
Targeting reagents: MO1-ihhb (1), MO2-ihhb (1), MO3-ihhb (1)
PHENOTYPE
Data: 3 figures from Chung et al., 2013
Observed in: glioblast (sensu Vertebrata) cell division, spinal cord glioblast (sensu Vertebrata), spinal cord neuron, spinal cord oligodendrocyte (all 6) expand
DISEASE ASSOCIATED WITH ihhb HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
acrocapitofemoral dysplasia Acrocapitofemoral dysplasia 607778
brachydactyly Brachydactyly, type A1 112500
GENE ONTOLOGY
Ontology GO Term
Biological Process striated muscle cell development (more)
Cellular Component extracellular region (more)
Molecular Function hydrolase activity (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000320 (1)
  • InterPro:IPR001657 (1)
  • InterPro:IPR001767 (1)
  • InterPro:IPR003586 (1)
  • InterPro:IPR003587 (1)
  • InterPro:IPR006141 (1)
  • InterPro:IPR009045 (1)
  • InterPro:IPR028992 (1)
  • PROSITE:PS50817 (1)
  • Pfam:PF01079 (1)
  • Pfam:PF01085 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ihhb-001 (1) 1717
    ihhb-002 (1) 979
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ihhb
    Tg(hsp70l:ihhb-mCherry)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ihhbContained in: [BAC] CH211-237C6 (1) (order this)
    ihhbContains: [SNP] rs3727945 (1), rs3727946 (1)
    ihhbEncodes: [cDNA] MGC:113262 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131088 (1) 1479bp
    Genomic GenBank:CU655960 (1) 153771bp
    Select Tool
    Polypeptide UniProtKB:F1R9L0 (1) 412aa
    Sequence Clusters UniGene:75090 (1)
    Sequence Information (all 18)
    OTHER ihhb GENE PAGES
  • Gene:30299 (1)
  • VEGA:OTTDARG00000034594 (1)
  • Ensembl(GRCz10):ENSDARG00000058815 (1)
  • ORTHOLOGY for ihhb (Chr: 6)
    Species Symbol Chromosome Accession # Evidence
    Human IHH 2
  • Gene:3549
  • OMIM:600726
  • HGNC:5956
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Ihh 1
  • MGI:96533
  • Gene:16147
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (71)