|
ZFIN ID: ZDB-GENE-980526-112
|
| Gene Name: |
islet1 |
| Gene Symbol: |
isl1 |
|
Previous Names:
|
Isl-1 (1),
islet-1
|
GENE EXPRESSION
| All Expression Data: |
178
figures
from
127 publications
|
| Directly Submitted Expression Data: |
6
figures
(12
images)
from Thisse et al., 2005
[eu243]
|
| |
6
figures
(12
images)
from Thisse et al., 2004
[MGC:73031]
|
| Wild-type Stages, Structures: |
Gastrula:Bud (10.0h-10.33h)
to
Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
|
| |
central nervous system,
cranial ganglion,
cranial nerve IX,
cranial nerve V
(all 77)
central nervous system,
cranial ganglion,
cranial nerve IX,
cranial nerve V,
cranial nerve VI,
cranial nerve VII,
cranial nerve X,
diencephalon,
dorso-rostral cluster,
endocrine pancreas,
epibranchial ganglion,
epiphysis,
epiphysis primary neuron,
facial nerve motor nucleus,
forebrain,
glossopharyngeal ganglion,
hatching gland,
head mesenchyme,
hindbrain,
hypothalamus,
interneuron,
liver,
mesoderm,
MiP motor neuron,
motor neuron,
nervous system,
neural plate,
neural rod,
neural tube,
neural tube motor neuron,
neural tube ventral region,
neuron,
oculomotor nucleus,
optic vesicle,
pancreas,
pancreas primordium,
pancreatic bud,
pharyngeal arch,
polster,
posterior lateral plate mesoderm,
posterior pancreatic bud,
presumptive neural retina,
primary interneuron,
primary motor neuron,
primary neuron,
proneural cluster,
retina,
retinal ganglion cell,
retinal ganglion cell layer,
retinal inner nuclear layer,
rhombomere,
rhombomere 2,
rhombomere 4,
rhombomere 4 motor neuron,
rhombomere 6,
rhombomere 7,
Rohon-Beard neuron,
RoP motor neuron,
secondary motor neuron,
spinal cord,
spinal cord neural rod Rohon-Beard neuron,
spinal cord neural rod primary neuron,
spinal cord neural tube motor neuron,
statoacoustic (VIII) ganglion,
telencephalon,
telencephalon ventral region,
trigeminal ganglion,
trigeminal motor nucleus,
trigeminal placode,
trigeminal placode primary neuron,
trochlear motor nucleus,
trunk,
unspecified,
vagal lobe,
ventral thalamus anterior region,
ventro-rostral cluster,
whole organism
|
| Curated Microarray Expression: |
GEO (1)
|
MUTANTS AND TARGETED KNOCKDOWNS
| Mutant lines: |
7 genotypes
|
| Alleles: |
rw436,
sa29
|
| Knockdown reagents: |
MO1-isl1
(1),
MO2-isl1
(1),
MO3-isl1
(1),
MO4-isl1
(1),
MO5-isl1
(1)
(all 6)
MO1-isl1
(1),
MO2-isl1
(1),
MO3-isl1
(1),
MO4-isl1
(1),
MO5-isl1
(1),
MO6-isl1
(1)
|
PHENOTYPE
| Data: |
8 figures
from
2 publications
|
| Observed in: |
atrial cardiac muscle cell differentiation,
atrium cardiac muscle cell,
heart,
heart contraction
(all 11)
atrial cardiac muscle cell differentiation,
atrium cardiac muscle cell,
heart,
heart contraction,
locomotion,
motor neuron axon,
pectoral fin motor nerve axon,
peripheral nervous system neuron axonogenesis,
post-vent region,
Rohon-Beard neuron axon,
whole organism
|
TRANSCRIPTS
| Type |
Name |
Length (bp) |
Analysis
|
|
|
mRNA
|
isl1-001
(1)
|
2303
|
|
|
GENE PRODUCT DESCRIPTION
CONSTRUCTS WITH SEQUENCES FROM isl1
|
Tg(2isl1-hsp70l:GFP),
Tg(2isl1:GFP),
Tg(3isl1:GFP),
Tg(4isl1:GFP),
Tg(hsp70l:isl1)
(all 17)
Tg(2isl1-hsp70l:GFP),
Tg(2isl1:GFP),
Tg(3isl1:GFP),
Tg(4isl1:GFP),
Tg(hsp70l:isl1),
Tg(isl1-hsp70l:dnplxna4-GFP),
Tg(isl1-hsp70l:GFP),
Tg(isl1-hsp70l:trpm7-EGFP),
Tg(isl1.2:Gal4-VP16,14xUAS:KikGR),
Tg(isl1:Gal4,14xUAS:KikGR,14xUAS:Mmu.Wlds),
Tg(isl1:Gal4-VP16,14xUAS:EGFP),
Tg(isl1:Gal4-VP16,14xUAS:Kaede),
Tg(isl1:Gal4-VP16,14xUAS:KikGR),
Tg(isl1:Gal4-VP16,UAS:EGFP),
Tg(isl1:Gal4-VP16,UAS:RFP),
Tg(isl1:GFP),
TgBAC(isl1:Gal4ff)
|
SEGMENT (CLONE AND PROBE) RELATIONSHIPS
Request: