ZFIN ID: ZDB-GENE-980526-562
Gene Name: ISL LIM homeobox 2a
Gene Symbol: isl2a
Sequence Ontology ID : SO:0000704

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Previous Names: isl2, zfIsl-2, wu:fc29g02

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 83 figures from 57 publications
Directly Submitted Expression Data: 6 figures (17 images) from Thisse et al., 2005 [eu308]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ca20 Insertion Unknown Frameshift, Premature Stop TALEN
ca21 Small Deletion Unknown Frameshift, Premature Stop TALEN
sa24713 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24714 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 9 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH isl2a HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001781 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00478 (1)
  • PROSITE:PS50023 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF00412 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM isl2a
    MARKER RELATIONSHIPS
    isl2aEncodes: [EST] eu308 (1), fc29g02
    [cDNA] MGC:193978 (1) (order this), MGC:193993 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130970 (1) 1713bp
    Genomic GenBank:CABZ01056691 (1) 12610bp
    Polypeptide UniProtKB:B3DH43 (1) 359aa
    Sequence Clusters UniGene:281 (1)
    Sequence Information (all 32)
    OTHER isl2a GENE PAGES
  • Alliance (1)
  • Gene:30157 (1)
  • Ensembl(GRCz11):ENSDARG00000003971 (1)
  • ORTHOLOGY for isl2a (Chr: 25)
    CITATIONS (104)