Gene
fscn2a
- ID
- ZDB-GENE-110901-1
- Name
- fascin actin-bundling protein 2a, retinal
- Symbol
- fscn2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Predicted to be involved in actin filament bundle assembly; cell migration; and establishment or maintenance of cell polarity. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 30. Is expressed in eye. Orthologous to human FSCN2 (fascin actin-bundling protein 2, retinal).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chou et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 30 | Alliance | Retinitis pigmentosa 30 | 607921 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin-crosslinking | Fascin | Fascin domain | Fascin, metazoans |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M6YWM1
|
485 | ||||
|
UniProtKB:B2LT49
|
488 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fscn2a-201
(1)
|
Ensembl | 1,467 nt |
Interactions and Pathways
No data available
Plasmids