Gene
sin3aa
- ID
- ZDB-GENE-070620-3
- Name
- SIN3 transcription regulator family member Aa
- Symbol
- sin3aa Nomenclature History
- Previous Names
-
- sin3a
- zgc:162128
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of Sin3-type complex. Predicted to be active in chromatin. Human ortholog(s) of this gene implicated in chromosome 15q24 deletion syndrome. Orthologous to human SIN3A (SIN3 transcription regulator family member A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| chromosome 15q24 deletion syndrome | Alliance | Witteveen-Kolk syndrome | 613406 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Histone deacetylase interacting domain | Paired amphipathic helix | Paired amphipathic helix superfamily | Sin3, C-terminal | Transcriptional regulatory protein Sin3-like |
|---|---|---|---|---|---|---|
|
UniProtKB:A5D6S0
|
1276 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sin3aa-201
(1)
|
Ensembl | 5,189 nt | ||
| mRNA |
sin3aa-202
(1)
|
Ensembl | 357 nt |
Interactions and Pathways
No data available
Plasmids
No data available