Gene
ptprfb
- ID
- ZDB-GENE-060503-530
- Name
- protein tyrosine phosphatase receptor type Fb
- Symbol
- ptprfb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have protein tyrosine phosphatase activity. Involved in sensory neuron axon guidance. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hyperinsulinism. Is expressed in liver and nervous system. Orthologous to human PTPRF (protein tyrosine phosphatase receptor type F).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
?Breasts and/or nipples, aplasia or hypoplasia of, 2 | 616001 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
Domain | IPR000242 | Tyrosine-specific protein phosphatase, PTPase domain |
Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
Domain | IPR003598 | Immunoglobulin subtype 2 |
Domain | IPR003599 | Immunoglobulin subtype |
Domain | IPR003961 | Fibronectin type III |
Domain | IPR007110 | Immunoglobulin-like domain |
Domain | IPR013098 | Immunoglobulin I-set |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype | Immunoglobulin subtype 2 | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | Tyrosine-specific protein phosphatase, PTPase domain | Tyrosine-specific protein phosphatases domain |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3APM3
|
1904 | |||||||||||||
UniProtKB:A0A8M3B069
|
1918 | |||||||||||||
UniProtKB:A0A8M3AQ61
|
1825 | |||||||||||||
UniProtKB:A0A8M9QC31
|
1807 | |||||||||||||
UniProtKB:A0A8M3B7N0
|
1900 | |||||||||||||
UniProtKB:A0A8M3B074
|
1802 | |||||||||||||
UniProtKB:A0A8M3B7M8
|
1921 | |||||||||||||
UniProtKB:A0A2R8QDC8
|
1913 | |||||||||||||
UniProtKB:A0A8M3AQ53
|
1927 | |||||||||||||
UniProtKB:A0A8M3AQ56
|
1919 | |||||||||||||
UniProtKB:A0A8M3AX63
|
1923 | |||||||||||||
UniProtKB:A0A8M9Q0G3
|
1817 | |||||||||||||
UniProtKB:A0A8M3APL8
|
1923 | |||||||||||||
UniProtKB:A0A8M9QPW8
|
1798 | |||||||||||||
UniProtKB:A4IFW2
|
1909 | |||||||||||||
UniProtKB:A0A8M9QH96
|
1917 | |||||||||||||
UniProtKB:A0A8M9QLG3
|
1813 | |||||||||||||
UniProtKB:A0A8M9QC27
|
1811 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
ptprfb-201
(1)
|
Havana | 7679 nt | |
mRNA |
ptprfb-202
(1)
|
Havana | 442 nt | |
ncRNA |
ptprfb-003
(1)
|
Havana | 524 nt |
Interactions and Pathways
No data available
Plasmids