Gene

id4

ID

ZDB-GENE-051113-208

Name

inhibitor of DNA binding 4

Symbol

id4 Nomenclature History

Previous Names

Id4 (1)
cb547 (1)
fb77d04
sb:cb547
wu:fb77d04
zgc:123214 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have protein dimerization activity. Involved in atrioventricular canal development; atrioventricular valve development; and regulation of Wnt signaling pathway involved in heart development. Predicted to localize to nucleus. Is expressed in central nervous system; heart; and retina. Orthologous to human ID4 (inhibitor of DNA binding 4, HLH protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb547 (16 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Ahuja et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With id4 Human Ortholog

No data available

Associated With id4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Family	IPR026052	DNA-binding protein inhibitor
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily