Gene
ahr1b
- ID
- ZDB-GENE-050922-1
- Name
- aryl hydrocarbon receptor 1b
- Symbol
- ahr1b Nomenclature History
- Previous Names
-
- ahr1 (1)
- si:dkey-159d6.1
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and ligand-activated transcription factor activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and response to xenobiotic stimulus. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Is expressed in eye. Orthologous to human AHR (aryl hydrocarbon receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Ulin et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
retinitis pigmentosa 85 | Alliance | ?Retinitis pigmentosa 85 | 618345 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000014 | PAS domain |
Domain | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Domain | IPR013655 | PAS fold-3 |
Domain | IPR013767 | PAS fold |
Domain | IPR033348 | Aryl hydrocarbon receptor, basic helix-loop-helix domain |
Family | IPR039091 | Aryl hydrocarbon receptor/Aryl hydrocarbon receptor repressor |
Homologous_superfamily | IPR035965 | PAS domain superfamily |
Homologous_superfamily | IPR036638 | Helix-loop-helix DNA-binding domain superfamily |
Repeat | IPR001610 | PAC motif |
Domain Details Per Protein
Protein | Length | Aryl hydrocarbon receptor/Aryl hydrocarbon receptor repressor | Aryl hydrocarbon receptor, basic helix-loop-helix domain | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | PAC motif | PAS domain | PAS domain superfamily | PAS fold | PAS fold-3 |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q4U3K9
|
940 |
Interactions and Pathways
No data available
Plasmids
No data available